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Effect of Moderate Altitude (>1000 m.a.s.l.) on Sleep Examinations (Polysomnography).

Recruiting
18 - 70 years of age
Both
Phase N/A

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Overview

The purpose of this study is to investigate the effect of moderate altitude (>1000 m.a.s.l.) on sleep examinations (polysomnography).

Description

Polysomnographies will be done for each participant for 2 consecutive nights at the sleep laboratory in Chur (CH; 600 m.a.s.l.) as well as for 2 consecutive nights at the participants home elevations (CH; >1000 m.a.s.l.). Between the measurements at those two different altitudes there will be a two-week washout period at >1000 m.a.s.l.. The sequence of altitude exposure will be randomized.

Eligibility

Inclusion Criteria:

  • Healthy (no current medical condition or intake of regular medication, except negligible medical issues or accidents not interfering with the current health status or physical performance.)
  • Living above 1000 m.a.s.l. since at least 1 year
  • No overnight stay at altitudes <1000 m.a.s.l. in the previous 4 weeks
  • 18-70 years old
  • Body mass index 18,5-30 kg/m2
  • informed consent

Exclusion Criteria:

  • Active diseases or health related conditions that require treatment (sleep disorders (mainly sleep apnea), chronic rhinitis, cardiovascular and lung diseases)
  • Use of drugs that affect the respiratory center drive (sedatives, sleep inducing drugs, opioids), stimulants or illegal drugs
  • Regular consumption of recreational drugs (alcohol and nicotine included)

Study details

Healthy

NCT05826808

Tsogyal Latshang

25 January 2024

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