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Symptomatic Carotid Outcomes Registry

Symptomatic Carotid Outcomes Registry

Non Recruiting
40 years and older
All
Phase N/A

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Overview

The purpose of this study is to build upon trials done over 30 years ago, which did not include statins, new antiplatelet agents, and newer antihypertensive medications. Since the landmark trials (NASCET, ECST), there have been new developments in medical stroke prevention, which creates a gap in knowledge. The aim of this study is to evaluate that clinical care with Intensive Medical Therapy (IMT) alone, the one year stroke rate in patients with symptomatic carotid stenosis and low risk clinical features will be <5%.

Description

This study will only be evaluating clinical care and no interventions will be done specifically for this research.

  • Informed consent from patient or legally authorized representative.
  • Participant survey/questionnaire completion at baseline, 6 and 12 months after enrollment
  • All data collected will be entered into a secure research data registry created for this study.

Study details
    Carotid Stenosis
    Ischemic Stroke
    Transient Ischemic Attack

NCT05300737

University of Maryland, Baltimore

21 October 2025

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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