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Insulin Clinical Trials

A listing of Insulin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 544 clinical trials
K Kurt Kristensen, MD, PhD

INfluenza VaccInation To Mitigate typE 1 Diabetes

In a multicenter, prospective, randomized, controlled clinical trial to compare influenza vaccination and placebo in sustaining β cell function in early type 1 diabetes mellitus.

7 - 17 years of age All Phase 4
L Leah Benn, MPH

Cellular Therapy for Type 1 Diabetes Using Mesenchymal Stem Cells

The goal of this study is to determine the safety and efficacy of fresh metabolically active allogeneic umbilical cord-derived mesenchymal stromal cells (UC-MSCs) for the treatment of new-onset type 1 diabetes (T1D) and to understand the mechanisms of protection. If proven effective, such a strategy can be used as a …

18 - 40 years of age All Phase 1
R Rebecca Leone

Healthy Outcomes for Muscle With Exercise in T1D

Over 300,000 people in Canada suffer from Type 1 Diabetes (T1D), a chronic condition whose incidence rate has been increasing in Canada every year by 5.1% (higher than the global average). While exogenous insulin injections allow those with T1D to live, it is not a cure, and those with T1D …

18 - 65 years of age All Phase N/A
T Tara Wilmot, RDN

Efficacy and Safety of a Ketogenic Diet in Type 1 Diabetes

Despite strong evidence that tight control of blood sugar reduces the risk of diabetes complications, most people with type 1 diabetes do not achieve recommended blood sugar targets. This randomized controlled trial will test whether a very-low- carbohydrate ketogenic diet can effectively and safely improve blood sugar control in adults …

18 - 65 years of age All Phase N/A

Treatment of Pre-diabetic State in Pediatric Population With Treg Cell Preparations and Rituximab

The main purpose of the study is to check: Can therapy with a preparation of regulatory cells (Tregs lymphocytes) and/or an anti-CD20 antibody preparation (rituximab) be successfully used in children with pre-diabetes to treat or delay type 1 diabetes? Is therapy with a preparation of regulatory cells (Tregs lymphocytes) and/or …

6 - 16 years of age All Phase 2

Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes

The goal of this clinical trial is to test the effects of a ketogenic diet on the progression and control of type 1 diabetes in children with newly diagnosed diabetes. The main questions to answer are: Does a ketogenic diet prolong the honeymoon period of type 1 diabetes? Does a …

5 - 12 years of age All Phase N/A

Safety of ENC-201-CED ENCRT

The purpose of the study is to evaluate the safety and tolerability of ENC-201-CED in a subcutaneous space in patients with Type I diabetes.

18 - 70 years of age All Phase 1

Pharmacist Led Educational Intervention on QOL, Medication Adherence & Satisfaction on Patients With Type 1 DM

There was no previous study in Iraq to evaluate the efficacy of pharmacist-led educational intervention on patient glycemic control, quality of life and medication adherence among type 1 diabetic patients in Iraq. Improving diabetes patients' information's about their disease control, the role of insulin and the right technique to administer …

16 years of age All Phase N/A
R Reid McClure, MSc

Fasted Exercise Training in Type 1 Diabetes (FED-T1D)

This study compares aerobic exercise training performed before breakfast (i.e., in the fasted state) to similar training performed after breakfast in people with type 1 diabetes. Training will take place over 12 weeks.

18 - 55 years of age All Phase N/A
K Keri Whitaker

Closed Loop and Education for Hypoglycemia Awareness Restoration

The purpose of the CLEAR study is to determine the effect on counterregulatory responses (CRR) of intervening (by attempting to strictly avoid hypoglycemia) to improve awareness of hypoglycemic symptoms among adults with type 1 diabetes (T1D) who have impaired awareness of hypoglycemia (IAH). IAH affects 20-25% of adults with T1D, …

18 - 75 years of age All Phase N/A

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