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Insulin Clinical Trials

A listing of Insulin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 523 clinical trials
S Sorin Ioacara, MD, PhD

Evaluating the Efficacy and Quality of Life Impact of Transitioning to Advanced Hybrid Closed-Loop Insulin Pump Therapy in Romanian Children With Type 1 Diabetes Mellitus

The proposed study aims to demonstrate the potential benefits of transitioning T1DM children from predictive low glucose suspend insulin pump therapy to advanced hybrid closed-loop insulin pump therapy in Romania. Primary Outcome: Variations in HbA1c between baseline visit (V1 - 740G) and assessment visit following three months of 780G insulin …

7 - 17 years of age All Phase 4
N Nabil Abdul Rahim

Effect of Tele-exercise on Cardiorespiratory Fitness in Paediatrics

The goal of this clinical trial is to learn if telemedicine exercise programme can improve the cardiorespiratory fitness (how well your body delivers oxygen to muscles and organs) and insulin resistance in Asian children with low cardiorespiratory fitness levels. The main questions it aims to answers are: Does telemedicine exercise …

12 - 17 years of age All Phase N/A
E Emeka F Nnakenyi, MD

Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)

Obesity is a chronic disease of global public health concern, contributing to cardiovascular disease, type 2 diabetes and certain cancers. Currently approved anti-obesity drugs and surgery are expensive and not readily available in Nigeria. Metformin, approved for type 2 diabetes, has been shown to promote weight loss among obese patients …

20 - 59 years of age All Phase 3
E Emanuel Canfora, PhD

Acute Microbial Switch

In this project the investigators will test if it is possible to measure changes in intestinal gas production after supplementation of a complex fiber mixture over a 36 hour period in both lean normoglycemic individuals and individuals with insulin resistance and/or prediabetes with overweight when compared with a placebo Changes …

30 - 75 years of age All Phase N/A
S Sudip R Bajpeyi, PhD

Improving Glycemic Control With Electrical Stimulation in Mexican-Americans

Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels. Subjects will be provided with a standardized diet (55/15/30% CHO/PRO/FAT) prior to collection of pre-intervention data of insulin sensitivity. Individuals will then participate in an …

18 - 65 years of age All Phase N/A
A Ana M Arbelaez, MD

Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism

The purpose of the study is to provide access to 18F-DOPA PET to patients at Washington University and assess the utility of 18F-DOPA PET/MRI as a preoperative tool to detect and localize focal lesions in the pancreas that are causing hyperinsulinism.

years of age All Phase 2
B Bryant Keirns, PhD

The Movie Theater Study

Increasing attention has been paid to meals with unusual characteristics that are consumed on a semi-regular basis (e.g., "tailgating," pizza buffets). The purpose of this study is to describe the acute cardiometabolic effects of a cinema-style meal rich in refined sugar, total carbohydrate, and moderate in fat (i.e., soda, popcorn, …

18 - 45 years of age All Phase N/A

Effect of a Sugar Replacement on Blood Glucose Levels in Healthy Adults

Diabetes and cardiovascular disease account for millions of deaths per year. One of the risk factors for both conditions is high blood sugar, particularly after eating (postprandial hyperglycaemia). Lowering blood sugar levels after a meal is expected to have a positive effect on preventing metabolic and cardiovascular diseases and improving …

18 - 65 years of age All Phase N/A
R Recruitment Department

Dynamic in Vivo PET Imaging and ex Vivo Biopsies From Skeletal Muscle and Adipose Tissue to Investigate the Effects of Exercise on Insulin Resistance and Mitochondrial Energetics in Type 2 Diabetes

The overall aim of this pilot study is to investigate the effects of exercise training on skeletal muscle and adipose tissue insulin resistance in subjects with Type 2 Diabetes (T2D).

30 - 65 years of age All Phase N/A

Gene Expression Changes In Young and Geriatric Skin

This study does not involve any particular diagnosis. The goal of this research study is to explore the effects of artificial sunlight (ultraviolet B radiation; UVB) on the skin of young adults versus geriatric adults. Sunlight exerts many effects on the body. There is evidence that in response to ultraviolet …

21 years of age All Phase N/A

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