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Analgesia Clinical Trials

A listing of Analgesia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 467 clinical trials

Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy

A randomized double-blind placebo controlled trial comparing the effect of a combined ketorolac and lidocaine paracervical block with a standard lidocaine paracervical block on procedure related pain with office hysteroscopies.

18 years of age Female Phase 1

Virtual Contexts for Affective Modulation

This study investigates how spatial context and perceived controllability modulate pain, affective states such as anxiety, and motivated behavior. The study examines how control over pain and threat-related environments influences pain perception, state anxiety, associated autonomic responses, and behavior. The main questions it aims to answer are: Does having control …

18 - 55 years of age All Phase N/A
M Marta Szyszko du Bois d'Aische

Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty

The objective of this clinical trial is to compare two regional analgesia techniques in patients undergoing total knee arthroplasty: IPACK (Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee) vs selective tibial nerve block. The main question is whether one of these peripheral blocks is more …

18 years of age All Phase N/A
I InSun Park, MD

Dual-chamber Patient-controlled Analgesia for Postoperative Recovery

Postoperative nausea and vomiting (PONV) are the most common complications that can occur after general anesthesia. Postoperative use of opioids and morbid obesity have been reported as risk factors of PONV. In this study, the investigators aimed to compare the degree of postoperative side effects and pain control when an …

19 - 65 years of age Female Phase N/A
F Fatma E Elsamahy, Master

Ultrasound Guided Interscalene, Suprascapular and Anterior Glenoid Nerve Blocks on Diaphragmatic Excursion and Analgesia Following Arthroscopic Shoulder Surgery

This study aims to evaluate the diaphragmatic movement and postoperative analgesia following anterior glenoid, suprascapular, and interscalene nerve blocks in patients undergoing elective arthroscopic shoulder surgery.

21 - 65 years of age All Phase N/A
R Roberto Tarud

Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy

This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid). This technique aims to block the hepatic branches of the celiac plexus to improve visceral pain control and its associated clinical …

18 years of age All Phase 4
I Isabel Kristan

Psilocybin in Cancer Pain Study

The overall objective of this study is to assess the feasibility, safety and preliminary efficacy of psilocybin-assisted therapy to alleviate opioid-refractory pain in patients with advanced-cancer. The name of the study intervention used in this research study is: Psilocybin (a tryptamine derivative)

18 years of age All Phase 2

Evaluating The Efficacy Of Pecs II Blockade Compared To Local Anesthetic Infiltration In Controlling Postoperative Pain In Patients Undergoing Oncologic Breast Surgery Under Opioid Free/Sparing Anesthesia.

Breast cancer is the malignant neoplasm with the highest incidence in women in Brazil, with the exception of non-melanoma skin tumors. Breast cancer surgery is an important part of treatment and post-operative pain needs to be adequately prevented and treated. This prospective, randomized, double-blind clinical study aims to evaluate the …

18 - 80 years of age Female Phase N/A
M Mustafa Sırrı Kotanoğlu, Associate Professor

Comparison of the Postoperative Analgesic Effects of SPSIPB and TPB in Mastectomy Operations

Breast cancer is the most common malignancy in women, and surgery is one of the cornerstone treatments for breast cancer. Postoperative pain can significantly reduce patients' quality of life and acute pain may even trigger chronic pain syndrome. Nerve blocks reduces opioid consumption in the postoperative period by providing better …

18 - 80 years of age Female Phase N/A

Opioid-Free Pain Control Regimen Following Robotic Radical Prostatectomy

The objective of this study is to conduct a randomized clinical trial to evaluate an opioid versus an opioid-free pathway of perioperative use of ketamine, ketorolac, and IV acetaminophen followed by the postoperative use of ketorolac, and oral acetaminophen for pain associated with robotic-assisted radical prostatectomy. Escalation to use of …

40 - 75 years of age Male Phase 2/3

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