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Analgesia Clinical Trials

A listing of Analgesia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 479 clinical trials
E Erzurum RTRH

M-Tapa Block and Transversus Abdominal Plane Block for Postoperative Analgesia in Unilateral Open Inguinal Hernia Repair Surgery

Patients will be called to the operating room one hour before surgery and no premedication will be applied before coming to the operating room. Patients in both groups who are taken to the block room will be administered 1-2 mg iv midazolam for sedation. M TAPA block will be applied …

18 - 65 years of age All Phase N/A
F Florent LEVIEL, MD

Non-steroidal Anti-inflammatory Drugs in Pleurodesis

Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended in a multimodal pain management to reduce pain intensity and to spare opioid use. However, there is a controversy in its use in pleurodesis surgery as it could block the process of pleurodesis in surgical pneumothorax. In addition, NSAIDs could increase the risk of …

18 years of age All Phase 2
M Marta Szyszko du Bois d'Aische

Pericapsular Nerve Block Versus Intrathecal Morphine for Analgesia After Primary Hip Arthroplasty

The aim of this clinical trial is to compare the analgesic effect of pericapsular nerve block (PENG) with intrathecal morphine in patients scheduled for total hip replacement surgery. The main question to be answered is whether the PENG block is equivalent to intrathecal morphine in reducing postoperative pain. Participants will …

18 years of age All Phase N/A
D Daniel Larach Larach, MD, MSTR, MA

Low-dose Buccal Buprenorphine: Relative Abuse Potential and Analgesia

The goal of this study is to compare the abuse potential of low-dose equianalgesic buccal buprenorphine to a commonly used full mu opioid receptor (MOR) agonist in a highly controlled experimental setting. This is a translational study in which healthy participants are phenotyped for psychosocial and Opioid-Use-Disorder-risk-related metrics. In a …

18 - 65 years of age All Phase 4
K Kajsa Bohlin, MD

Surfactant Administration by Insure or Thin Catheter

This trial evaluates the efficacy and safety of surfactant administration with thin catheter technique together with analgesic premedication in comparison with the established INSURE-strategy. It will provide valuable knowledge to improve clinical methodology and enhance lung protective treatment strategies for preterm infants.

- 2 years of age All Phase N/A
H Hojin Lee, MD, PhD

Intrathecal Morphine Injection Versus Continuous Wound Infiltration After Pancreaticoduodenectomy

This is a prospective randomized open-label noninferiority trial that compares intrathecal morphine injection and continuous wound infiltration after open pancreaticoduodenectomy.

19 years of age All Phase N/A
T Tuba Yılmazer, PhD

Effect of Breathing Exercise on Pain and Quality of Recovery in After Transplantation Patients: A Randomized Controlled Trial

The researchers will fill out the "Patient Introduction Form" for the patients who agreed to participate in the study after obtaining permission from the experimental group with the "Informed Consent Form" the day before the surgery. The breathing exercises will be taught and monitored by the researchers, and the researcher …

18 - 65 years of age All Phase N/A
B Buyun Xu

Effects of Music During Atrial Fibrillation Ablation Under Conscious Sedation

I. Background Atrial fibrillation, a common type of arrhythmia, is often treated with radiofrequency catheter ablation, a minimally invasive procedure that helps restore a normal heart rhythm. While this surgery is typically performed under "light sedation" (where patients remain semi-awake) and allows for quick recovery, many patients still experience significant …

18 - 80 years of age All Phase N/A
Z Zuo Xiangrong

Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated Patients

A prospective, randomized controlled study was conducted to compare the effects of esketamine combined with dexmedetomidine in the sedation and analgesia treatment of mechanically ventilated patients in the ICU on the time to awaken, time to extubation, time to mechanical ventilation, time in the ICU, and on delirium.

18 - 70 years of age All Phase 4
A Anesthesia, Pain Management and Surgical ICU Department

Erector Spinae Block Vs Ketamine-based Multimodal Analgesia Protocol in Lumber Decompressive Surgery

The aim of this study is to compare the quality of recovery of the erector spinae plane block (ESPB) versus ketamine-based multimodal analgesia regimen after spine decompressive surgery.

20 years of age All Phase N/A

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