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Edgbaston Birmingham, United Kingdom Clinical Trials

A listing of Edgbaston Birmingham, United Kingdom clinical trials actively recruiting patients volunteers.

Found 147 clinical trials
S Susanne Seifert

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

HDClarity will seek at least 2500 research participants at different stages of Huntington's disease (HD). The primary objective is to collect a high quality CSF sample for evaluation of biomarkers and pathways that will enable the development of novel treatments for HD. The secondary objective is to generate a high …

11 - 75 years of age All Phase N/A

Avacostar - (PASS)

The Avacostar PASS is a non-interventional, multi-national, prospective cohort study that will collect data from 2 cohorts of patients: those treated with avacopan for active severe AAV, and a second cohort treated with a cyclophosphamide or rituximab-based induction regimen without avacopan for active severe AAV. The overall study duration is …

18 years of age All Phase N/A
K Kathy Page, BSc(Hons)

Gaucherite - A Study to Stratify Gaucher Disease

The purpose of this research is to review data already collected and to collect new data from adults and children in England with Gaucher Disease to determine clinical factors which predict severity and response to therapy of Gaucher disease especially in the areas of bone, cancer and brain conditions.

years of age All Phase N/A

The PEACE (Posthumous Evaluation of Advanced Cancer Environment) Study

Historically, cancer research has been limited by sample acquisition in late stage disease, often restricted to single sites of disease with limited parallel clinical data collection in terms of prior therapy exposure. The PEACE study is intended to facilitate tissue donation from multiple tumour sites in the post-mortem setting and …

18 years of age All Phase N/A
T Tracey Willis, Prof

A Review of the Management and Outcomes of Children With SMA in the West Midlands During 2017-2022

Spinal Muscular Atrophy (SMA) is a rare neuromuscular condition, characterised by loss of motor neurons as a result of a mutation in the survival motor neuron gene. This results in muscle wasting and in the most common and severe type, death before 24 months. Over the recent years there has …

- 16 years of age All Phase N/A
J Jack Hamer

Placental Characteristics Within Monochorionic Twin Pregnancies

This prospective study aims to collate a comprehensive database of all main monochorionic twin groups to enable comparisons to be made within each twin group and additionally between each group with regards to several placental characteristics, whilst understanding their impact on several fetal outcomes. This study aims to provide new …

years of age Female Phase N/A
T The Chief Investigator

ICONIC: Improving Outcomes Through Collaboration in OsteosarComa

There has been little improvement in outcome for patients with osteosarcoma (OS) over the last 20 years. There have been only a few clinical trials of new treatments and no major new therapies introduced recently. This is in part because there is no good understanding of the biology of osteosarcoma, …

years of age All Phase N/A

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