Advanced Filters
noise

Edgbaston Birmingham, United Kingdom Clinical Trials

A listing of Edgbaston Birmingham, United Kingdom clinical trials actively recruiting patients volunteers.

Found 147 clinical trials

The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII (ACCoRd)

Study design: Randomised, controlled, multi-centre, open-label, phase III trial (with a single intervention registration phase). Primary Objectives The primary objectives of this study are to determine: The impact on Depth of Response (DoR: less than VGPR versus VGPR or better) when salvage ASCT conditioning is augmented by the addition of …

18 years of age All Phase 3

A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease

The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of a single dose of ALN-HTT02.

25 - 70 years of age All Phase 1
S Senior Haematology Research Sister

Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial

The goal of this clinical trial is to test the ability to restore gut microbiota to healthier levels in patients with blood cancers scheduled to have stem cell transplant. The main questions it aims to answer are: Tolerability and acceptability of intestinal microbiota transplantation (IMT) versus placebo (as assessed via …

18 years of age All Phase 2
L Luiza Bivolaru

Relationships in Good Hands - Clinical and Cost-effectiveness of Dyadic Developmental Psychotherapy

The research question is: Can the research recommend better ways for social care and health services to work work together to help adoptive and foster families? Can a therapy called DDP improve the mental health of 5-12 year old fostered or adopted children? Is DDP worth the commitment families need …

5 - 12 years of age All Phase N/A

FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis

FARGO is a randomised, phase IIa, multi-centre, placebo-controlled trial to compare Faecal Microbiota Transplant (FMT) with placebo in patients with primary sclerosing cholangitis (PSC) and concomitant inflammatory bowel disease.

18 years of age All Phase 2
J James Wolffsohn

Protecting the Eyes of Gamers With Lubricating Eyedrops

The excessive use of screens particularly amongst digital gamers can adversely impact the health of the surface of the eyes with symptoms and signs of surface damage. While strategies including limiting screen time exist, these may be ineffective given the widespread rise of digital device use and gaming culture in …

18 years of age All Phase N/A
S Sunil Shah, Phd

Impact of Tixel Treatment on Symptoms and Signs in Patients with Dry Eye Disease

This study will examine how a standard Tixel treatment versus a sham treatment for eye wrinkles affects the symptoms and signs of Dry Eye Disease.

18 years of age All Phase N/A

Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

The purpose of this study is to evaluate the efficacy and safety of AZD5148 for prevention of recurrence of Clostridioides difficile infection in Individuals 18 years of age and above.

18 years of age All Phase 2
R Ramya Ramanujachar

A Multi-Arm, Platform Trial For Relapsed Neuroblastoma

Neuroblastoma is one of the most common solid childhood tumours, and a major cause of cancer-related death in children. More than 1200 children/young adults a year are diagnosed in USA and Europe. Around 600 of these cases are considered high-risk, which means the cancer is more difficult to treat successfully. …

1 years of age All Phase 1/2

GLycaemic Outcomes With Whey Protein in ageING

The goal of this placebo-controlled, partial crossover design study is to identify the impact of consuming whey protein before meals on free-living glucose control in older adults living with type 2 diabetes. The primary specific objective is to determine the effect of a thrice daily whey protein pre-meal supplementation at …

75 - 90 years of age All Phase N/A

Simplify language using AI