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Ealing, United Kingdom Clinical Trials

A listing of Ealing, United Kingdom clinical trials actively recruiting patients volunteers.

Found 750 clinical trials

Comparative Effectiveness and Safety of ELIOS in Patients With Open-Angle Glaucoma Undergoing Cataract Surgery

The primary study objective is to compare the effectiveness of the combination of phacoemulsification with intraocular lens implant with ELIOS or competitor device in reducing IOP at 12 months postoperatively.

40 years of age All Phase N/A
C Caroline Ovadia, Doctor

Impact of Cold Exposure on Metabolic Regulation in Children With Non Alcoholic Fatty Liver Disease (NAFLD)

The aim of this project is to generate pilot data for a grant proposal to evaluate the impact of intermittent cold exposure (ICE) on brown and white adipose tissue (BAT/WAT) function in children with non-alcoholic fatty liver disease (NAFLD). The condition NAFLD is the most common liver disease in both …

8 - 26 years of age All Phase N/A
E Ethaar El-Emir, PhD

Spirometry Interpretation Performance of Primary Care Clinicians With/Without AI Software

To evaluate whether an artificial intelligence decision support software (ArtiQ.Spiro) improves the diagnostic accuracy of spirometry interpreted by primary care clinicians, as measured by Clinician Diagnostic Accuracy (vs Reference Standard).

18 - 99 years of age All Phase N/A
A Annegret H Dahlmann-Noor, PhD

Red Light Ptosis Proof-of-Concept

This study tests a new treatment to help with droopy eyelids (ptosis) and eye movement problems (squint) in children and young people with genetically confirmed mitochondrial conditions - using red-light. We use a torch to shine a red light through the closed eyelid for 3 minutes a day. The study …

3 - 18 years of age All Phase N/A
G Gill Radcliffe, PhD

IMV to Accelerate Recovery of Lung Function in Veno-venous Extracorporeal Membrane Oxygenation; Lung Rest Or Moderate Mechanical Ventilation in ECMO

Feasibility trial to inform a future multicentre randomized control trial. The investigators aim to evaluate the feasibility of a trial of near apnoeic ventilation (two breaths per minute) compared with standard ventilation (respiratory rate between 10 and 30 breaths) for patients with acute respiratory distress syndrome (ARDS) supported with veno-venous …

18 years of age All Phase N/A

Role of Cytosorb in Left Ventricular Assist Device Implantation

Mechanical circulatory support, specifically implantable continuous flow left ventricular assist device (CF-LVAD) therapy has been established as a viable treatment for rapidly deteriorating patients suffering from end stage heart failure either as bridge or alternative to heart transplantation. However, a large proportion of these patients experience severe complications in the …

18 - 70 years of age All Phase N/A
C Crispin Hiley

Hemithoracic Irradiation With Proton Therapy in Malignant Pleural Mesothelioma

Phase III randomised-controlled trial for patients with unilateral malignant pleural mesothelioma (MPM).

18 years of age All Phase N/A

Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial

Glaucoma is the leading cause of sight impairment and blindness worldwide. It is a long-term eye disease which can cause permanent loss of sight and sometimes blindness and affects 1 in 50 people over 50 years of age. Open-angle glaucoma (OAG) is the most common type of glaucoma. This tends …

18 years of age All Phase 3
P Prapa Kanagaratnam, PhD

Ablation of Focal Activation in Atrial Fibrillation

Recurrent focal electrical activation (or ectopy) superseding sinus activation is the only mechanism proven to drive paroxysmal atrial fibrillation (AF). However, it has not been possible to show similar focal drivers during AF, owing to the limitations of mapping in persistent AF. RETRO-Mapping has been developed as a method to …

18 - 85 years of age All Phase N/A
N Neeraj Shah

Assessment of Volume-targeted Ventilation in Patients With Neuromuscular Disease

Assessment of safety and efficacy of volume-targeted ventilation in patients with neuromuscular disease.

18 - 80 years of age All Phase 2

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