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Ealing, United Kingdom Clinical Trials

A listing of Ealing, United Kingdom clinical trials actively recruiting patients volunteers.

Found 750 clinical trials

UK ENcorafenib and BInimetinib Real-world Study in Melanoma

This is a prospective longitudinal multi-centre observational study conducted in the United Kingdom, in patients with metastatic cutaneous BRAF V600 mutation-positive melanoma assigned to receive encorafenib and binimetinib. The aim of this study is to learn about how encorafenib and binimetinib perform, patients' experiences of using them, and how they …

18 years of age All Phase N/A

Assessing Cancer Treatment Response to Therapy Using 18F-FSPG PET

Prospective single centre non-randomised exploratory observational study to measure changes in tumour cellular redox status with 18F-FSPG PET in stage 3 non-small cell lung cancer (NSCLC) and stage 3 and 4 head and neck squamous cell cancer (HNSCC) at baseline and during standard of care treatment, and to compare this …

16 years of age All Phase N/A

Early DiAgnosis Real-Time Healthcare System for CANcer Trial

The purpose of the study is to assess whether the AI characterisation system of the CADDIE device improves the endoscopists accuracy in the optical diagnosis of diminutive colorectal polyps in the bowel during colonoscopy. Participants will either have a colonoscopy with the assistance of the CADDIE device characterisation AI system …

18 years of age All Phase N/A
K Kimberley Morlese

DERMATOMICS: Identifying Regulators of Skin Homeostasis

Diseases of the skin associated with chronic immune driven conditions, including scleroderma, lupus, dermatomyositis, psoriasis, and atopic dermatitis, significantly impact skin integrity, function, and overall quality of life. These conditions can lead to severe disfigurement, discomfort, and systemic complications, necessitating long-term medical intervention. The prevalence of these skin disorders is …

18 years of age All Phase N/A
C Chris Carswell, PHD, FRCP

White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)

Idiopathic Normal Pressure Hydrocephalus (iNPH) is a progressive condition of the elderly that results in severe disability. iNPH can dramatically respond to Cerebral spinal fluid(CSF)-shunting where excess ventricular fluid is diverted from the brain. Not all patients with iNPH respond to CSF-shunting however. The reasons for this are uncertain. Aim …

60 years of age All Phase N/A
S Sushma Saxena, B.Tech, Msci

AI-Driven Early Detection of Skin Cancer

This study evaluates the feasibility and accuracy of an AI-powered mobile platform (NuvanaDx) for early detection of skin cancer, including melanoma, using smartphone-based imaging. The platform is designed to improve access to early diagnosis, reduce waiting times, and support triage into appropriate care pathways.

18 years of age All Phase N/A
A Aileen O'Brien

Novel VR Intervention for Use in Psychiatric Inpatient Wards

The current study aims to examine the feasibility and acceptability of a VR app for use on inpatient psychiatric wards. The study will be completed in two stages. Stage One is a co-design stage. A virtual reality hypnotherapy app that has been developed in collaboration with the company Phase Space, …

18 - 65 years of age All Phase N/A
M Mark Pandrich, MBBS

Early Versus Late Monitoring Among Pregnant Women With a History of Gestational Diabetes

The goal of this study investigate if pregnant women with a history of gestational diabetes (GDM) have better pregnancy outcomes if they test their blood glucose four times a day early in the pregnancy versus having an oral glucose tolerance test later in the pregnancy at 28 weeks in their …

17 - 45 years of age Female Phase N/A

An Observational Study of Predictors and Outcomes of Lung Cancer in Never-smokers in the UK

The goal of this observational study is to improve the early detection of lung cancer in adults who have smoked less than 100 tobacco cigarettes ("never-smokers") in the United Kingdom. The main questions it aims to answer are: To describe characteristics such as demographics, co-morbidities and environmental exposures To describe …

18 years of age All Phase N/A
C Chris Gale

Health-Related Quality-of-Life and Household Financial and Wellbeing Impacts of Prematurity and Necrotising Enterocolitis (NEC).

PREM-IMPACT is a UK-based observational study exploring how caring for a very premature baby-particularly one affected by necrotising enterocolitis (NEC)-impacts families over the first year after hospital discharge. NEC is a serious bowel disease that can occur in premature babies, often requiring surgery and prolonged hospitalisation. This study runs alongside …

- 30 years of age All Phase N/A

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