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Tokyo and Other Japanese City, Japan Clinical Trials

A listing of Tokyo and Other Japanese City, Japan clinical trials actively recruiting patients volunteers.

Found 65,447 clinical trials
C Chuanxu Liu, MD

Predictive Factors for the Efficacy of CD19 CAR-T Therapy in Relapsed/Refractory Large B-Cell Lymphoma: A Clinical Study

This is a single-center real-world study aiming to explore predictive factors for the efficacy of CAR-T therapy in patients with relapsed/refractory large B-cell lymphoma (R/R LBCL).

18 years of age All Phase N/A

Pediatrics Mobile CT

A special kind of CT scanner that can move around (called a mobile CT) is already approved by the FDA to take pictures of adult and pediatric heads. This study wants to see if the same machine can safely take pictures of the chest and belly (abdomen) in children. This …

- 5 years of age All Phase N/A
W Wenjin Yin

Trastuzumab Deruxtecan in Advanced Breast Cancer

To evaluate the efficacy and safety of trastuzumab deruxtecan in advanced breast cancer patients.

18 years of age All Phase N/A
M Mathilde mathilde.herber@chru-strasbourg.fr, MD

Study of a Cohort of Non-HIV Immunocompromised Patients With Toxoplasmosis at the Strasbourg University Hospital

Toxoplasmosis in HIV-positive individuals is well-studied and has a codified management protocol, which is not the case for other immunodeficiencies, except for recent recommendations in the context of hematopoietic stem cell transplantation. A description of this population is necessary to estimate the number of patients affected and to define their …

18 years of age All Phase N/A

Efficacy Analysis of Personalized-Target Transcranial Magnetic Stimulation (TMS) in the Treatment of Chronic Tinnitus: A Single-Center, Single-Blind Randomized Clinical Trial

The goal of this clinical trial is to evaluate the efficacy and safety of personalized-target transcranial magnetic stimulation (TMS) in the treatment of chronic subjective tinnitus. The study aims to determine whether stimulation at individualized auditory cortex targets, identified by resting-state functional MRI, provides greater therapeutic benefit compared with conventional …

18 - 80 years of age All Phase N/A
C Courtney Mangus, M.D.

Text-based Support for Parents of Adolescents Following an Emergency Department Visits

The goal of this study is to determine the effectiveness of an adaptive text-based intervention for parents of adolescents seeking emergency department services for suicide risk concerns.

13 years of age All Phase N/A
H Herui Yao

A Study of BRY812 for Injection Alone in Subjects With Advanced Malignancies

This is a Phase I, multicenter, open-label, single-arm and first-in-human clinical study of BRY812 for injection. The study objectives are to evaluate the safety, tolerability, pharmacokinetic profile, anti-tumor activity and immunogenicity of BRY812 for injection in patients with advanced malignancies. Patients will receive treatment every 3 weeks until intolerable toxicity, …

18 years of age All Phase 1
M Min Yan, Professor

A Study of A166 in Patients With HER2-Positive Unresectable or Metastatic Breast Cancer

Evaluation of the efficacy of A166 in Patients with HER2-Positive unresectable or metastatic breast cancer previously treated with TOP1 inhibitor Antibody-Drug Conjugates

18 - 75 years of age All Phase 2
E Evgeny E Zharkov

Combined Method of Surgical Treatment of Anal Fissure

The purpose of this study is to improve treatment outcomes for patients with chronic anal fissure.

18 - 70 years of age All Phase N/A
Y Yao Yao

Dual-target BCMA-CD19 CAR-T Cell Therapy for RR/MM With Extramedullary Infiltration

This is a multicenter, open-label, non-randomized, single-arm clinical trial. Patients with relapsed/refractory multiple myeloma accompanied by extramedullary infiltration will receive BCMA - CD19 CAR-T cell therapy. The primary objective is to prospectively evaluate the safety of dual-targeting BCMA and CD19 CAR - T cell therapy for extramedullary infiltration in relapsed/refractory …

18 - 75 years of age All Phase 1

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