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Tokyo and Other Japanese City, Japan Clinical Trials

A listing of Tokyo and Other Japanese City, Japan clinical trials actively recruiting patients volunteers.

Found 65,447 clinical trials
D Debby Schommer, RN, CCRC

RELIVE (Randomized Evaluation of Less Invasive Ventricular Enhancement) Trial

A prospective, multi-center randomized trial comparing the Revivent System plus GDMT to GDMT alone. A total of approximately 135 subjects will be randomized in a 2:1 allocation ratio (90 treatment and 45 control), with approximately 128 evaluable patients and assuming 5% loss to follow-up. A primary safety endpoint will be …

18 years of age All Phase N/A

RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative

The purpose of this sham-controlled pilot randomized controlled trial (RCT) is to evaluate the feasibility, safety, and preliminary efficacy of a one-month intervention consisting of 20 home-based active or sham RS-tDCS sessions paired with audio track guided mindfulness meditation practice in otherwise healthy adults seeking to reduce cannabis use in …

22 - 65 years of age All Phase N/A

A Phase 1 Study of CLYM116 in Normal Healthy Volunteers

This Phase 1, first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of CLYM116 in healthy volunteers.

18 - 60 years of age All Phase 1
G Gabriel Honnef, MD

Implementation of an Empiric Transfusion Bundle for Out of Hospital Patients With Haemorrhagic Shock

The investigators will evaluate the implementation of a treatment bundle (Fibrinogen, Plasma and Tranexamic Acid)

18 years of age All Phase N/A
S Stacey Sigmon, Ph.D.

Food Insecurity and Eating Behavior Among Adults Receiving Buprenorphine or Methadone Maintenance Treatment: Pilot Study 2

The goal of this study is to evaluate the effects of a novel, mail-based meal delivery intervention among individuals receiving MOUD on household food security status. The main question it aims to answer is: Will participants randomized to the NE+MD intervention will demonstrate greater reductions in USDA FSS scores from …

18 years of age All Phase N/A
T Tenia Heigh

A Biomarker Study in Men With Localized Prostate Cancer Treated With Aglatimagene Besadenovec

Phase 2a, open-label, multi-center study evaluating biomarkers and biodistribution of aglatimagene besadenovec plus valacyclovir in men with localized, favorable intermediate-risk prostate cancer who are planning to receive external beam radiation therapy (EBRT).

18 years of age Male Phase 2
D Dr Ayesha Wahid, Fcps

Comparison Between Oral Methotrexate and Tofacitinib in Chronic Plaque Psoriasis

Psoriasis is a chronic inflammatory dermatoses which include well demarcated scaly erythematous plaques on whole body including scalp role of methotrexate vs tofacitinib is compared in this study

18 - 70 years of age All Phase 0
S Sandrine Foucras

ELUDYN: Assessment of Intra-individual Variability of Vascular Dynamics of Gadopiclenol Injection Parameters in Contrast-enhanced MRI

This study aims to understand how the volumes and speeds of intravenous injection of a recent type of contrast agent can be optimized in order to improve the information provided by medical images. To do this, five MRI scans lasting approximately 30 minutes will be performed on 10 healthy volunteers …

18 - 40 years of age All Phase 4
M Michela Moscarino

Delayed Pelvic Imaging With [68]Ga-PSMA PET/CT in a Patient With High-risk Prostate Cancer.

Recent evidence suggests that both standard-time and delayed-time \[⁶⁸Ga\]Ga-PSMA PET acquisitions can reveal clinically relevant findings, and neither phase should be excluded a priori in routine practice. This study evaluates a streamlined dual-phase protocol consisting of: A standard whole-body PET/CT acquisition performed 60 minutes after radiotracer administration. A delayed pelvic …

30 years of age Male Phase N/A
Y Yanfei Professor Liu, Doctoral Degree

A Study of BR111 in Patients With Advanced Malignancies

This is a Phase I, multicenter, open-label, single-arm and first-in-human clinical study of BR111-101 for injection. The study objectives are to evaluate the safety, tolerability, pharmacokinetic profile, anti-tumor activity and immunogenicity of BR111-101 for injection in patients with advanced malignancies.

18 years of age All Phase 1

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