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mild-cognitive-impairment Clinical Trials

A listing of mild-cognitive-impairment medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 678 clinical trials
J Jessica Wiles

Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery

The goal of this clinical trial (Balanced-2 study) is to compare light to deep general anesthesia using widely available brain monitors, to see if 'light' anesthesia could reduce rates of delirium, cognitive decline, and disability in older adults undergoing major surgery. Delirium is the most common serious surgical complication, occurring …

55 years of age All Phase N/A
Y Yan Bi, MD,PhD

China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study (China-DECODE Study)

Type 2 diabetes (T2D) and dementia are both diseases with increasing incidence and prevalence globally, leading to substantial economic burdens for families and society. Notably, diabetes significantly increases the risk of cognitive dysfunction, which is classified into preclinical stage, mild cognitive impairment and dementia based on the disease severity. Cognitive …

45 years of age All Phase N/A
S Sipei Pan Dr.

Study on Aging and Cognitive Impairment in China

Background: By the end of 2022, China had about 280 million people aged 60 and older, making up 19.8% of the population. This number is projected to exceed 300 million by the end of the 14th Five-Year Plan and 400 million by 2035, which would be over 30%. The 20th …

years of age All Phase N/A
D Defei Chen

Association Between Blood Pressure and Risk of PSCI

This retrospective cohort study was designed to explore the relationship between blood pressure and cognitive impairment after stroke

18 - 90 years of age All Phase N/A
K Kee-hyung Park

Korean Joint Registry for Alzheimer's Treatment and Diagnostics (JOY-ALZ)

The purpose of this research is to investigate the long-term effectiveness and safety of new Alzheimer's disease treatments, particularly monoclonal antibody therapies like lecanemab and donanemab, as well as to enhance diagnostic methods for Alzheimer's disease by collecting real-world data from Korean Alzheimer's patients. The goal is to contribute to …

19 years of age All Phase N/A

InRAD Observational Study

The goal of this international observational study is to evaluate long-term disease outcomes and treatment safety in people with Alzheimer's disease (PwAD), by collecting real-world data from routine clinical practice across global clinical centers. The InRAD Registry Observational Study has several aims: To collect medical information for many years from …

years of age All Phase N/A
M Mayra Macias

TabCAT Brain Health Assessment in Primary Care

Efficient and user-friendly paradigms to detect cognitive impairment, including dementia are needed in primary care. The TabCAT Brain Health Assessment accurately detects cognitive impairment via an appealing tablet interface with automated scoring and EMR integration. This study will evaluate the effectiveness of the paradigm on detection rates and other brain …

18 years of age All Phase N/A
E Erica Weiss, PhD

5-Cog 2.0: A Pragmatic Clinical Trial

Cognitive impairment related to dementia is frequently under-diagnosed in primary care settings. This problem is more prevalent in health disparities populations. The investigators developed the 5-Cog brief cognitive assessment that is simple to use, standardized, takes \<5 minutes, does not require informants, and accounts for major technical, cultural, and logistical …

65 years of age All Phase N/A
Y Yansu Guo, Ph.D

The Beijing Longitudinal Disability Survey in Community Elderly

The goal of this observational study is to establish the prospective cohort of the Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE) to explore the high-risk factors and preventive interventions for disability and cognitive impairment among community-dwelling adults aged 65 years and over. The main question it aims to answer …

65 years of age All Phase N/A
W Wanpen Vongpatanasin, MD

Preventing Cognitive Decline by Reducing BP Target Trial

The PCOT study is a multi-site randomized trial of patients 70 years or older with high BP. The main goal of the study Preventing Cognitive Decline by Reducing BP Target Trial (PCOT) is to conduct a large pragmatic clinical trial (PCT) to test the hypothesis that patients who receive care …

70 years of age All Phase N/A

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