Advanced Filters
noise

mild-cognitive-impairment Clinical Trials

A listing of mild-cognitive-impairment medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 678 clinical trials
A Adina Maeir, PhD

Cog-Fun Ageing Participation-centered, Health Promotion for Older Adults

The goal of this feasibility study is to test the feasibility of a group intervention program based on health management principles for older adults with Subjective Cognitive Decline (SCD). SCD is a condition where individuals feel that their memory is worsening, although standard tests do not detect it. This perceived …

60 years of age All Phase N/A
y yaqin li

Exergame-assisted Simultaneous Motor-cognitive Training for Middle-aged Old Adults in China

To develop and conduct a pilot trial on the effectiveness of a technology-based (exergame) intervention approach for the middle-aged old adults' population in China. The study will examine the feasibility of the intervention and estimate its preliminary effects in improving their physical, cognitive, and dual-task performance.

50 - 60 years of age All Phase N/A
A Alejandro Padilla Isassi, Geriatrician

Impact of NANO-PSO on Cognition in Older Adults with Mild to Moderate Cognitive Impairment

The objective of this randomized, triple-blind, placebo-controlled clinical trial is to compare NANO-PSO therapy against placebo in improving cognitive abilities in older adults with mild to moderate non-vascular cognitive impairment over six months of treatment. The primary questions it aims to answer are: • Does NANO-PSO therapy improve cognitive abilities …

60 years of age All Phase 2
F FenLing Kuo, Master

Dance Intervention to Improve Executive Function and Physical Performance in Older Adults With Cognitive Impairment

This pilot study investigates the effects of a music-based dance intervention on executive function and physical performance in middle-aged and older adults with cognitive impairment. Dance, as a form of dual-task training, integrates music, rhythmic movement, and cognitive-motor coordination. When combined with group interaction and partner-guided physical cues, it has …

55 years of age All Phase N/A
L LiJun Chi

Study On the Expression Level and Clinical Significance of VISTA in Patients With Vascular Cognitive Impairment

1\. Explore the expression level of immune checkpoint VISTA in peripheral blood and cerebrospinal fluid of patients with cardiovascular risk factors; 2. Discuss the correlation between different risk factors (mainly hypertension, diabetes, smoking, hyperlipidemia, hyperhomocysteinemia, etc.) and the expression level of immune checkpoint VISTA in peripheral blood and cerebrospinal fluid …

50 - 80 years of age All Phase N/A
M Meltem Çapar, Specialst

The Effect of Reminiscence Therapy in Elderly

In this study titled "Psychological Well-Being and Awareness in the Elderly: The Effect of Reminiscence Therapy", patients will be randomly divided into two groups as experimental and control groups. No intervention will be made to the patients in the control group. Reminiscence therapy will be applied to the patients in …

65 - 100 years of age All Phase N/A

Acute Effects of THC in Older Adult

The primary objective of this study is to determine if increasing age confers greater vulnerability to the acute A) cognitive (e.g., memory, attention, psychomotor function), B) subjective (e.g., anxiogenic and rewarding effects), and C) cardiovascular (heart rate and blood pressure), effects of THC in adults \> 21 years old. The …

21 years of age All Phase 1
M Mona Kamal, Ph.D.

The Effects of Some Antihyperglycemic Drugs on Cognitive Function and Risk of Depression of Diabetic Patients

The study aims to investigate the effects of DPP-4 Is+ metformin versus SGLT2 Is + metformin on the risk of cognitive decline and depression in patients with T2DM.

55 years of age All Phase N/A

Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.

On pump coronary revascularization is a very common leading cause for post-operative cognitive dysfunction regarding patient age grouping and diffuse systemic inflammatory response induced by bypass machine . Many factors are incriminated as pre-operative sleep disturbance, previous history of neurocognitive dysfunction. The accumulating evidence refers to an incidence between 20-40% …

60 - 75 years of age All Phase 0
G Gong-Jun JI, Ph.D.

Safty and Efficacy of MCI Network Guided TMS for Early Alzheimer's Disease: A Randomized, Double-blind Trial

Estimate the safty and efficacy of personalized network neuronavigated transcranial magnetic stimulations in early Alzheimer's disease patients

45 - 85 years of age All Phase N/A

Simplify language using AI