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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,757 clinical trials
M Melyssa Godfrey

Effects of Breathing and Attention Training (BAT) on Pain Modulation

The hypersensitivity of fibromyalgia is associated with abnormal pain modulation within the CNS, but not with peripheral or central sensitization. Many brain areas that contribute to modulation of pain are known, but their testing is complex and expensive. Quantitative sensory testing is easier to perform and repeatable. Therefore, it will …

18 - 70 years of age All Phase N/A
J Jeanna Julo, BA

Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain

Donor site pain study comparing post-operative donor site pain and opioid consumption after use of Lidocaine, Liposomal Bupivicaine or regional nerve block for split thickness skin graft harvesting in patients with less than 20% TBSA burn wounds and less than %5 Deep partial or full thickness burn wounds.

18 years of age All Phase 4
H Hannah O'Brien, MHA

REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss

The purpose of this research study is to learn how two different supportive programs may help women feel better after surgery. This study will measure if one type of supportive program is more useful than the other for improving wellbeing after surgery.

18 years of age Female Phase 3
J John Hughes

Wearable Device to Increase Physical Activity Amongst Adults With Pain

This protocol is for a pragmatic mixed methods randomized parallel-group exploratory feasibility trial to examine all facets of a proposed future phase III trial on the use of wearable device to increase physical activity and possibly reduce pain amongst middle-aged people with musculoskeletal (MSK) chronic pain. The feasibility study is …

40 - 65 years of age All Phase N/A
A Aimee Pehrson

ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy

The purpose of this study is to investigate the use of the erector spinae (ESP) block in reducing the morphine milligram equivalent (MME) consumption post percutaneous nephrolithotomy. Objectives: - Determine if there is a significant effect on post percutaneous nephrolithotomy MME consumption with the usage of an ESP block vs. …

18 years of age All Phase N/A
S Simne M Nunes, MSc

YOga for Patients With Chronic BACK Pain and Poor PROgnosis

The goal of this clinical trial is to investigate the effectiveness of yoga for patients with chronic low back pain and high risk of poor prognosis. The main question it aims to answer is In patients with back pain and high risk of poor prognosis, what is the effectiveness of …

18 - 60 years of age All Phase N/A
A Anna Kelli, MSc

High Frequency RF Current Effects on Muscle Pain and Function

The purpose of this study is to examine the acute and chronic effects of high frequency electrical current transfer (frequently called "TECAR") on pain and functional movement in individuals with a musculoskeletal injury or pain. The participants will be assigned into an experimental or a control group and outcome measures …

18 - 65 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain

Morton s neuroma is an irritation of the nerves that affect the feet. People with this condition may have burning or shooting pain in the balls of their feet. They may also have numbness in adjacent areas. These symptoms may become more frequent and severe over time. The pain may …

18 years of age All Phase 1
H Hannah Palanchi

Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury

The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.

18 years of age All Phase N/A

RCT of Pain Perception With Fast and Slow Tenaculum Application

This project will be a randomized controlled trial (RCT) measuring pain perception with two different tenaculum placement techniques on the uterine cervix. A tenaculum is an instrument used to hold the cervix (the opening to the uterus or womb) in place. The trial will measure pain perception with a Visual …

18 years of age Female Phase N/A

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