Advanced Filters
noise

pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,825 clinical trials
L LHMC Department of Anesthesiology

Reducing Pain With Methadone and Ketamine in Liver Transplant

The goal of this clinical trial is to learn if using methadone and ketamine during an adult deceased donor liver transplant can help decrease pain after surgery. The main questions it aims to answer are: What impact does using methadone and ketamine during a deceased donor liver transplant have on …

18 years of age All Phase 4
J Julian Gingold, MD PhD

Paracervical Block for Pain Reduction in Saline Infusion Sonograms

Inadequate pain management during gynecologic procedures is a growing women's health concern, especially as it reduces access to care for patients who may subsequently avoid further treatment. Although recent evidence has shown that local anesthesia reduces pain during certain gynecologic procedures, such as intrauterine (IUD) placements, there is still limited …

18 - 50 years of age Female Phase 4
A Anne M McKenzie-Brown, MD

Low Dose Naltrexone for Pain in Patients With HIV

The increased life expectancy of Patients Living With HIV/AIDS (PLWHA) has increased the need for therapies for chronic conditions, such as chronic pain. Pain in the HIV population is often refractory and ends up being treated with chronic opioids, which are associated with adverse effects, including hyperalgesia, constipation, and risk …

18 - 65 years of age All Phase 4
B Behnam Liaghat, PhD

Exercise in Patients With Hypermobile Joints and Knee Pain

Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving activity-related pain in young patients (18-45 years) with hypermobile joints and knee pain.

18 - 45 years of age All Phase N/A
M Monique van Velzen, PhD

The Impact of Psilocybin on Pain in Fibromyalgia Patients

Rationale: Recent evidence shows that Lysergic Acid Diethylamide (LSD), even when administered in low, non-hallucinogenic doses, can produce analgesic effects and improve pain tolerance in a sample of healthy volunteers. Such results complement what was already observed with other serotonergic psychedelics such as psilocybin: survey studies and case series indicate …

18 - 65 years of age All Phase N/A
C Chen Chih-I

2% Lidocaine Gel in Reducing Postoperative Pain Following Haemorrhoidectomy

The study is a randomized, double-blind, controlled trial evaluating the efficacy of 2% lidocaine gel in reducing postoperative pain and analgesic consumption after haemorrhoidectomy. 222 patients undergoing Ferguson haemorrhoidectomy will be randomly assigned to receive either 2% lidocaine gel or a non-anaesthetic lubricant gel control. Pain scores using a visual …

18 - 80 years of age All Phase N/A
C Chi Wai Cheung, MBBS, MD

Peripheral Stimulation of Acupuncture Points for Low Back Pain

For decades, chronic low back pain has been one of the major health complaints in Hong Kong. Without proper management, low back pain is associated with functional disability and decreased quality of life. However, currently, there is still no "gold standard" treatment for cure of the problem.

18 years of age All Phase N/A
L Lisa Martin, MSC

Study of Lipid Mediators in Chronic Postoperative Pain - LICP

This interventional prospective study aims firstly to investigate variations in lipid levels in blood samples and their potential relationship with the duration and/or intensity of post-operative pain. Secondly, it aims to investigate the activation of peripheral blood mononuclear cells and neutrophils in patient blood samples. The study will enrol women …

18 years of age Female Phase N/A
F Fadi MQ Al Zoubi, PhD

Art Therapy for Adults With Chronic Low Back Pain

This project aims to assess the feasibility and preliminary efficacy of a supervised group-based art intervention for adults with chronic low back pain (CLBP).

18 - 59 years of age All Phase N/A

Meditation for Older Adults With Chronic Low Back Pain

This pilot randomized controlled trial aims to recruit 66 community-dwelling older adults with chronic low back pain and follow up them for 8 weeks. This study aims to test the preliminary effect of a mindfulness-based meditation (MBM) intervention on pain and symptoms among community-dwelling older adults with chronic low back …

50 - 89 years of age All Phase N/A

Simplify language using AI