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bone-diseases Clinical Trials

A listing of bone-diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 80 clinical trials
y yinzhi y liu, master

Exosome microRNAs as Potential Biomarkers of Metabolic Bone Disease of Prematurity

Metabolic bone disease of prematurity (MBDP) is caused by insufficient content of calcium, phosphorus, and organic protein matrix in preterm infants or bone metabolism disorder, which is one of the complications affecting the quality of life of preterm infants. The early symptoms of MBDP are insidious, and there is no …

- 72 years of age All Phase N/A
V Virginia Kimonis, MD

Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)

The investigators are researching families with inherited inclusion body myopathy (IBM) and/or Paget disease of bone (PDB) and/or dementia (FTD) which is also called IBMPFD. IBMPFD is caused by mutations in the VCP gene. Our main goal is to understand how changes in the VCP gene cause the muscle, bone …

18 years of age All Phase N/A
C Claudia Erika Delgado Espinoza, MD, Ph D

3D Printing Models in Surgical Planning of Osteotomies in Kienbock´s Disease Stages II-III

Ischemic necrosis of lunate bone, osteonecrosis or Kienböck´s disease was described by Kienböck in 1910. Numerous surgical procedures for this disease had been proposed. These surgical options, that depends of the radiological stage and anatomical risk factors, can be classified into lunate unloading procedures, lunate revascularization, replacement procedures and salvage …

18 - 85 years of age All Phase N/A
S Salah A. Hegazy, PhD

Four Locator Attachment Mandibular Overdentures

. There is little information on the degree of crestal bone loss around 4 inter-foraminal implant-retained mandibular overdentures (OVDs) and the amount of bone remodelling on the anterior maxilla and posterior mandibule on long-term function, particularly with different distributions.

55 - 80 years of age All Phase N/A

Evaluation of Faisability, Safety and Effectiveness and of Discogel in Patients With Aneurysmal and Simple Bone Cysts

There is no consensus in the scientific literature for the treatment of aneurysmal and simple bone cysts. Some scientific articles with utilisation of sclerosis agents for the treatment of aneurysmal bone cysts: Ethibloc no longer marketed, pure Ethanol, Aetoxisclerol.

years of age All Phase N/A
D Doaa A. Mewafy, PhD

Four Mandibular Implant-retained Overdentures in Individuals With Type 2 Diabetes

Studies clinically evaluate the long-term outcome of 4 implant attachment-retained mandibular OVDs among patients with high glycemic levels are lacking.

55 - 65 years of age All Phase N/A

Knee Related Subchondral Bone Lesions Treated With IOBP

The study will be a prospective, multicenter clinical study evaluating clinical and patient reported outcome measures of subjects receiving IOBP® surgical technique using Angel cPRP and BMA processing system to treat subchondral bone pathology (SBP).

18 - 60 years of age All Phase N/A
D Didier MAINARD, Pr

BONE SUBSTITUTES OUTCOMES

A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all TEKNIMED Bone Substitute range of products: CERAFORM, TRIHA+, NANOGEL, and all their private labels. TEKNIMED bone substitutes are legacy products, some marketed for more than 20 years. Their performance and safety have already been …

18 years of age All Phase N/A

Gait Analysis and Degenerative Spine

The goal of this observational study is to analyse the biomechanics of a degenerative spinal disease. The main questions it aims to answer are: What are the biomechanical variables affected by the disease How they evolve with disease progression and treatment

50 - 85 years of age All Phase N/A
i ismail demirkale

Adductor Ratio in Severe Varus Gonarthrosis

The restoration of the joint line (JL) is essential for the proper functioning of Total Knee Arthroplasty (TKA). The exact position of JL can be determined using anatomical landmarks such as femoral condylar width (TEW), tibial tubercle, fibular head, and adductor tubercle during preoperative planning or intraoperatively. However, in cases …

65 years of age All Phase N/A

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