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bone-diseases Clinical Trials

A listing of bone-diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 80 clinical trials
X Xin-yi Cai, MD.

Cardiovascular-Kidney-Metabolic Syndrome in Shanghai Zicitizens

The main purpose of this study is to conduct follow-up assessments and update the cardiorenal outcomes among the STONE cohort that was established during 2016-2017. The secondary aim is to compare metabolic risk factors, metabolic disturbances, and clinically relevant metabolic outcomes between the follow-up period and the baseline assessment. The …

18 years of age All Phase N/A

Fosfomycin i.v. for Treatment of Severely Infected Patients

The purpose of this European, multicentric, prospective, non-interventional study is to document and evaluate the efficacy and safety of the treatment of severely infected patients with intravenously administered fosfomycin, including patients with osteomyelitis, complicated urinary tract infection, nosocomial lower respiratory tract infection, bacterial meningitis/central nervous system infection, bacteraemia/sepsis, skin and …

18 years of age All Phase N/A
T Thomas Edouard, MD, PhD

Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies

The aim of this project is to set up a biological and clinical collection of patients with progressive bone, calcium and growth plate pathologies. This collection will provide a better understanding of the mechanisms involved in growth plate and bone damage in these diseases and identify factors predictive of progression …

- 99 years of age All Phase N/A
O Ozlem M Goker-Alpan, MD

Biomarkers Related to Bone in Pediatric Gaucher Disease

Aims of the observational study is to establish novel blood-based biomarkers for grading bone disease in pediatric patients with Gaucher disease (GD). Patients with clinically confirmed GD: deficient GCase enzyme activity and corresponding genetic analysis will be eligible for enrollment. Levels of Lyso-Gb1, chitotriosidase, and CCL18 will be established for …

5 - 21 years of age All Phase N/A
V Virginia Kimonis, MD

Characterization of Familial Myopathy and Paget Disease of Bone

The researcher wants to explore the genetic causes of muscle disease. The researcher is particularly interested in muscle disorders that occur in combination with diseases of bone that appear to be passed on from generation to generation. Diffuse Optical Spectroscopy will measure the concentrations of blood, water, and lipids (fats, …

18 years of age All Phase N/A

Deep Phenotyping of Bone Disease in Type 2 Diabetes and Relations to Diabetic Neuropathy

Objectives The goal of this cross sectional clinical trial is to examine the phenotype of bone disease in type 2 diabetes.The main aims are to: Compare bone microarchitecture, bone biomechanical competence, and bone turnover markers as well as postural control in T2D patients with and without fractures. Examine how autonomic …

40 years of age All Phase N/A
B Barbara Rocca

Low Back Pain and Osteopathy in Italian Young People

This is a behavioral observational study aimed at evaluating the presence of low back pain in young people and the intention to undertake osteopathic treatments. It consists of a short self-administered questionnaire which will be given to adolescents with gnathological/orthodontics disorders to complete. Relationships between low back pain of young …

11 - 30 years of age All Phase N/A
N Nada Akad, Dr.

Assessment of Mineral and Bone Disorders in Kidney Transplant Recipients

This study aims to integrate bone measurements (including bone turnover markers (BTM), bone mineral density (BMD) measurement, vertebral fracture assessment (VFA), trabecular bone score (TBS) ) commonly used in the general population for primary osteoporosis evaluation to enhance the assessment of CKD-MBD.

20 - 70 years of age All Phase N/A
F Frédéric VELARD

Monocytes as Predictors of Cystic Fibrosis-related Bone Disease

Hypothesis: Circulating monocytes RANK and MCSF-R expression is predictive of Cystic Fibrosis-related Bone Disease. Study design: Single-center comparative cross-sectional study Population: Patients with a CFTR channel mutation causing cystic fibrosis consulting the Centre de Ressources et de Compétences de la Mucoviscidose (CRCM) at Reims University Hospital will be recruited. Healthy …

20 - 65 years of age All Phase N/A

Interest of the SPECT-CT Scan SUVspect in the New Generation of Gamma-cameras With Semiconductor

Since 2017, a revolution began in the departments of nuclear medicine, with the routine use of gamma-cameras with semiconductor. These gamma-cameras (which obtained the CE-marking in 2016), offer a technological breakthrough by providing an additional information. They allow "to quantify" for the 1st time in clinical routine conditions, the quantity …

18 years of age All Phase N/A

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