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intermittent-claudication Clinical Trials

A listing of intermittent-claudication medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 26 clinical trials
H Holly DeSpiegelaere

Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis

Peripheral artery disease (PAD) is a manifestation of atherosclerosis that produces progressive narrowing and occlusion of the arteries supplying the lower extremities. The most common clinical manifestation of PAD is claudication, i.e., a severe functional limitation identified as gait dysfunction and walking-induced leg muscle pain relieved by rest. The standard …

18 - 90 years of age All Phase 4
H Holly DeSpiegelaere

MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology

In our research, we are delving into whether taking MitoQ for six months can improve the symptoms and function of people diagnosed with peripheral artery disease, especially those who suffer from leg pain while walking, known as intermittent claudication. We will be checking if MitoQ helps people with claudication walk …

21 years of age All Phase N/A
S Silvia Innocenti

Study of the R3 Vascular Drug-Eluting Bioresorbable Scaffold in Treating Below the Knee Arterial Disease

This first-in-human clinical feasibility study will evaluate the safety and performance of the R3 Vascular MAGNITUDE® Bioresorbable Drug-Eluting Scaffold and Delivery System in patients undergoing treatment for peripheral arterial disease severe enough to have significantly reduced the blood supply to their leg. The severe reduction in blood flow causes lifestyle …

18 - 90 years of age All Phase N/A

CRUSH PAD: Real-world Outcomes Following Use of the Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions

The primary goal of the study is to obtain effect size data on the use of Shockwave Intravascular Lithotripsy (IVL) technology in calcified common femoral lesions in patients with peripheral artery disease for a series of endpoints, including target lesion revascularization and health status, to enable future planning of comparative …

18 years of age All Phase N/A
G Gabriele Heuer

Assessment of the Relationship Between Severity of Chronic Venous Obstruction and Venous Claudication

Assessment of the Relationship between Severity of Chronic Venous Obstruction and Venous Claudication

18 - 80 years of age All Phase N/A
S Stefano Scarano, MD, Research Fellow

Efficacy of Split Gait in the Treatment of Dynamic Asymmetries in Subjects With Pathologic Claudication

Walking on a split-belt treadmill (each of the two belts running at a different speed) imposes an asymmetrical gait, mimicking limping that has been observed in various pathologic conditions. This walking modality has been proposed as an experimental paradigm to investigate the flexibility of the neural control of gait and …

18 - 70 years of age All Phase N/A

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