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intermittent-claudication Clinical Trials

A listing of intermittent-claudication medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 29 clinical trials
C Chris Seenan

Motivating Physical Activity With Behavioural interVention and Electrical Stimulation Remotely in Intermittent Claudication

Peripheral Arterial Disease (PAD) is a common vascular disease which commonly causes limb pain and reduced exercise tolerance termed Intermittent Claudication (IC). People with PAD and IC have impaired quality of life, reduced walking ability, and increased mortality compared to those who do not have the condition. Improving physical activity …

18 - 100 years of age Both Phase N/A
S Shauneen Valliere, MSN, NP

The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication

This study will focus on people with claudication from peripheral arterial disease. The investigators are researching whether a multicomponent therapeutic can increase the production of Nitric Oxide in the blood and whether that leads to an improvement in pain free walking distance and overall physical activity.

18 - 100 years of age Both Phase 1

Contribution of Optical Coherence Tomography in the Endovascular Treatment of Femoral Occlusions

This is a common care study. A study for evaluating the quality of balloon inflation and stent application will be performed in 2D angiography alone in the control group and then by 2D and OCT angiography for the experimental group. The benefit could be an improvement in the results of …

18 - 100 years of age Both Phase N/A
V Valérie MONNIN-BARES, MD

Exercise Tolerance After Venous Recanalization for Post-thrombotic Syndrome

Post-thrombotic syndrome (PTS) is the most frequently observed chronic complication of deep vein thrombosis (DVT), with an estimated cumulative incidence of 20-50%. Endovascular venous recanalization with angioplasty and stenting of obstructive lesions is the recommended treatment option to reduce or correct the symptoms of DVT. However, its impact on the …

18 - 100 years of age Both Phase N/A

Paclitaxel Eluting Stent in Long SFA Obstruction: A Prospective, Randomized Comparison With Bypass Surgery

Chronic lower limb ischemia due to atherosclerosis causes significant morbidity especially in elderly: the prevalence of asymptomatic obstructive peripheral atherosclerosis among 40-74 old is 4-22%. The prevalence of its milder symptomatic manifestation, intermittent claudication among 40 years old men is about 1% and among 70 years old it is 7%. …

18 - 100 years of age Both Phase 3
A Ashley Solieri

REmotely Supervised Exercise Therapy Trial 2

Supervised exercise for intermittent claudication is a first line therapy for peripheral arterial disease, as recommended by the National Institute for Health and Clinical Excellence and the European Society for Vascular Surgery. However 2/3 of British trusts cannot implement this due to gym availability, costs, travel time and the requirement …

18 - 100 years of age Both Phase N/A
N Nicole L Lohr, MD PhD

Red Light Treatment in Peripheral Artery Disease

Subjects with a known diagnosis of peripheral artery disease as measured by an abnormal ankle brachial index (<.9 or >1.1) will undergo a single 5 min exposure of 670 nm light, 1 cm above the gastrocnemius muscle. Blood flow will be measured by infusion of ultrasound contrast and subsequent acquisition …

18 - 85 years of age Both Phase N/A

Effect of Breather in COPD Patients with Intermittent Claudication

The aim of this study To show the effect of breather on ventilatory and vascular function in COPD patient with intermittent claudication.

50 - 60 years of age Male Phase N/A
A Antonia PEREZ MARTIN, MD

VIRTUOSE : Efficiency of Sildenafil on the Absolute Claudication Distance of Peripheral Arterial Disease Patients With Intermittent Claudication.

Peripheral Arterial Disease (PAD) is a highly debilitating disease that affects 202 million people around the world and about 7 million people in France. Morbi-mortality from cardiovascular events is increased in this population. Intermittent claudication is defined as a discomfort and/or pain in the legs during walking. It is the …

18 - 100 years of age Both Phase 3
M Mads Sundet, MD

Additional Hyperbaric Oxygen After Lower Extremity Amputation

This study evaluates the effect of additional hyperbaric oxygen therapy after lower extremity amputation. The patients will be randomized after amputation to either a treatment group receiving hyperbaric oxygen therapy, or control group.

18 - 90 years of age Both Phase N/A

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