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spinal-cord-injuries Clinical Trials

A listing of spinal-cord-injuries medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 315 clinical trials
M Matthias J Krenn, PhD

Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury

People with spinal cord injuries may experience muscle tightness or uncontrollable spasms. This study is being conducted to investigate whether transcutaneous spinal stimulation can improve these symptoms. Transcutaneous spinal stimulation is a non-surgical intervention by applying electrical currents using skin electrodes over the lower back and belly. The investigators want …

18 years of age All Phase N/A
D Danira Garcia Gutierrez, BS

Vibrant Capsule for Spinal Cord Injury Neurogenic Bowel Dysfunction

The goal of this study is to test the safety and effectiveness of Vibrant capsules in spinal cord injury patients with neurogenic bowel.

21 years of age All Phase N/A

Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria

This is a Phase 1b study to assess the safety, tolerability, PK, and PD of investigational phage therapy (IP) in adults with SCI and bladder colonization (ASB). It is a single-center, randomized, double-blind, placebo-controlled study in adults with SCI with neurogenic bladders and bacteriuria who use indwelling catheters, or who …

18 years of age All Phase 1
H Hannah, MS, ACSM-EP

Hypoxia Pathways for Early Recovery After Spinal Cord Injury

Spinal cord injury (SCI) disrupts neural pathways to respiratory motor neurons, diminishing breathing capacity and airway defense (e.g., cough). Indeed, respiratory impairment is a leading cause of infection, re-hospitalization and death after SCI. There is a critical need for new strategies to restore breathing ability and airway defense in people …

18 - 70 years of age All Phase N/A
G Genevieve Madera, B.S.

Testosterone Deficiency and Endothelial Dysfunction After Spinal Cord Injury

Heart attacks and strokes are among the most common causes of premature death in individuals living with spinal cord injury (SCI) and appear to occur earlier in life. The factors that lead to the heighten and accelerated risk of heart attacks and strokes in adults living with SCI remain poorly …

18 - 89 years of age Male Phase N/A
K Karen Barnes

Neuromodulation After Spinal Cord Injury to Improve Limb Function

The University at Buffalo (UB) Department of Rehabilitation Sciences is looking for adult volunteers with and without spinal cord injuries for a study on hand movement. The goal of the study is to learn about how the brain, nerves, and muscles of the body are connected and perform everyday tasks. …

18 - 75 years of age All Phase N/A
D Daniel Lu, MD

Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury

This is a phase 1 study of safety and feasibility of cervical spinal cord stimulator implantation in cervical SCI subjects who are ventilator dependent. The Investigators will be focusing on the safety and feasibility of this approach. Participants may qualify for the study if they are male or female 18-75 …

18 - 75 years of age All Phase N/A
M Matthew T Maher, MS

Autonomic Effects of Spinal Cord Stimulation in Spinal Cord Injury

The goal of this interventional crossover study is to determine the effects of transcutaneous spinal cord stimulation (TSCS) on the ability to perform moderate exercise and regulate core body temperature in the chronic spinal cord injury community. The main questions it aims to answer are: What are the effects of …

18 years of age All Phase N/A
E Eduardo Bauer, MD

Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder

The purpose of this study is to determine if electric stimulation to the leg, called transcutaneous tibial nerve stimulation (TTNS), can improve bladder outcomes in acute spinal cord injury.

18 - 75 years of age All Phase N/A
E Elizabeth Felix, PhD

Association Between Body Composition and Pain in Spinal Cord Injury

The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and explore the influence of body composition on these responses, in individuals with chronic spinal cord injury

18 - 65 years of age All Phase N/A

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