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spinal-cord-injuries Clinical Trials

A listing of spinal-cord-injuries medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 315 clinical trials
G Gary J Farkas, PhD

Gut-Brain Neural Coupling in Spinal Cord Injury

The purpose of this research is to determine the effects of food on brain and stomach activity in persons with and without spinal cord injury (SCI).

18 - 70 years of age All Phase N/A
O Olive Lennon

Exoskeleton Training for Spinal Cord Injury Neuropathic Pain (ExSCIP)

The goal of this feasibility trial is to learn if exoskeleton or robotic walking works to reduce nerve (neuropathic) pain after spinal cord injury. This study asks is: Providing walking practice through use of a robotic device (exoskeleton) three times per week for twelve weeks possible to deliver? Would people …

18 - 90 years of age All Phase N/A
X Xue Jiang

Near-Infrared Imaging of Motor Imagery Effects in Spinal Cord Injury

The primary objective of this clinical trial is to investigate the efficacy of motor imagery-based brain-computer interface (MI-BCI) technology in improving motor function among patients with spinal cord injury (SCI), as well as its impact on cortical motor area function across varying states. To achieve this, the study will implement …

18 - 75 years of age All Phase N/A
M Monica Perez, PhD, PT

Double Dose 4-AP on Functional Recovery After Spinal Cord Injury

The purpose of this study is to test a strategy to potentiate functional recovery of lower limb motor function in individuals with spinal cord injury (SCI). The FDA approved drug, Dalfampridine (4-AP). 4-AP will be used twice-daily in combination of Spike-timing-dependent plasticity (STDP) stimulation and STDP stimulation with limb training.

18 - 85 years of age All Phase 1/2
D Deena Cilien, DPT

A Novel Repetitive Synchronized Associative Stimulation Neuromodulation Approach for Spinal Cord Injury Patients

The purpose of this research is to explore the effect of magnetic stimulation to activate the brain, electrical spinal cord stimulation to activate spinal cord, and electrical muscle stimulation used to activate upper limb (arms), lower limb (legs) and trunk (stomach) muscles in people with spinal cord injury (SCI) and …

18 - 70 years of age All Phase N/A
R Ruben I. Carino-Escobar, PhD

Efficacy of a Brain-Computer Interface Controlled Functional Electrical Stimulation Therapy for Spinal Cord Injury Neurorehabilitation

The study's main goal is to determine the efficacy of a therapy with brain-computer interface controlled functional electrical stimulation for neurorehabilitation of spinal cord injury patients' upper limbs. For this purpose, a randomized controlled trial will be performed to compare the clinical and physiological effects of the brain-computer interface therapy …

18 years of age All Phase N/A
M Mario Widmer, PhD

Robot-assisted Vs. Conventional Occupational Therapy of the Upper Limb in Individuals with Cervical Spinal Cord Injury

The goal of this clinical trial is to learn the effects of robot-assisted therapy using the ArmeoSpring on upper limb function compared to conventional occupational therpay in individuals with cervical spinal cord injury (cSCI). The main questions it aims to answer are: Which of the two forms of therapy, robot-assisted …

18 years of age All Phase N/A
L Leighann Martinez

Improving Balance After Spinal Cord Injury Using a Robotic Upright Stand Trainer and Spinal Cord Epidural Stimulation

The purpose of this study is to understand how standing and sitting balance control is altered after spinal cord injury and how a new type of robotic assistive device may be used with spinal stimulation to improve muscle function. The investigators will be testing a device called the Tethered Pelvic …

18 years of age All Phase N/A

A Study of Andecaliximab in People With Spinal Cord Injury at Risk for Bone Growth Outside of the Normal Skeleton.

This is an open-label study of andecaliximab in participants at risk of developing bone where bone should not be, such as in muscle, tendons, and other soft tissues following traumatic spinal cord injury. The goal of this study is to assess the safety of andecaliximab, how much drug is in …

18 - 89 years of age All Phase 1/2
D David Darrow, MD MPH

Epidural Stimulation After Neurologic Damage: Long-Term Outcomes

This study will evaluate the long-term effect of chronic spinal cord stimulation to restore volitional movement for patients with chronic spinal cord injuries.

22 years of age All Phase N/A

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