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spinal-cord-injuries Clinical Trials

A listing of spinal-cord-injuries medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 315 clinical trials
R Randy D Trumbower, PT, PhD

Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury

Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with chronic spinal cord injury (SCI). The goal of the study is to understand the mechanisms by which intermittent hypoxia enhances …

18 - 75 years of age All Phase N/A
S Steven Knezevic, MS

Seated Balance Using the Indego™

Exoskeleton-assisted walking (EAW) provides a new mobility option and appears to have potential therapeutic benefits for persons with SCI. However, present day technology is not sufficient to replace the wheelchair. During EAW, users stand upright, maintain static and dynamic balance by actively and passively stimulating trunk and lower limb muscles …

18 years of age All Phase N/A
L Lynsey Duffell, PhD

iCycle II: Recovery of Function Through FES Cycling With VR Biofeedback in People With SCI.

The annual incidence of traumatic spinal cord injury (SCI) is estimated at 2,500 (35 per week) in the UK and, due to advances in research and clinical management, the majority now have incomplete injuries, with significant potential for neurological improvement. Discovering ways to provide intensive, but cost-effective SCI rehabilitation is …

18 years of age All Phase N/A
I Ismael Seanez, PHD

Spinal Cord Stimulation and Training

This study will help the investigators better understand the changes in short-term excitability and long-term plasticity of corticospinal, reticulospinal and spinal neural circuits and how the changes impact the improvements of spinal cord stimulation (SCS) mediated motor function.

16 - 65 years of age All Phase N/A
U Ufedo Miachi

Upper Limb Spinal Cord Stimulation for Rehabilitation Enhancement

In the United Kingdom, there are more than 1000 new cases of spinal cord injury (SCI) each year, with around half of these injuries affecting the cervical spine. People who have reduced function and control affecting their upper limbs may have difficulty carrying out activities of daily living (ADLs), significantly …

18 years of age All Phase N/A
A Astrea Villarroel-Sanchez, MPH

Testosterone and Neural Function

Spinal cord injury (SCI) disrupts the nerves controlling movement, along with those that regulate functions like heart rate and blood pressure (known as the autonomic nervous system, or ANS). Testosterone (T) plays a significant role in brain health and ANS reflex function in non-neurologically impaired men. However, little is known …

18 - 80 years of age Male Phase N/A
L Lance Goetz, MD

Epidural Stimulation and Resistance Training After SCI

Spinal cord injury (SCI) is a devastating health problem for tens of thousands of military personnel, Veterans and civilians annually. Many persons with SCI must use a wheelchair for their entire life. A new scientific breakthrough called "lumbosacral epidural stimulation" or "ES" can help people with SCI to stand, step …

18 - 60 years of age All Phase 2/3
J Jocelyne Bloch, MD

Study on Preliminary Safety and Efficacy of Epidural Electrical Stimulation to Manage Lower Urinary Tract Dysfunction After Spinal Cord Injury

This clinical trial aims to assess the preliminary safety and efficacy of Epidural Electrical Stimulation (EES) therapy in managing lower urinary tract dysfunction in individuals with sub-acute or chronic spinal cord injury (SCI). The study evaluates the therapy's potential to improve urinary function and prevent neurogenic detrusor overactivity, ultimately seeking …

18 years of age All Phase N/A
M Megan Hammond, MEd

At-Home Genital Nerve Stimulation for SCI Bowel

The purpose of this study is to test whether electrical stimulation of the skin in the pelvic area (near the genitals) can reduce the reflexes that cause bowel accidents in people with spinal cord injuries. Current bowel treatments either involve diet and medications or surgery. This study will evaluate whether …

18 years of age All Phase N/A
D David Kim

Self-balancing Personal Exoskeleton for SCI

This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).

18 years of age All Phase N/A

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