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sleep-apnea-syndromes Clinical Trials

A listing of sleep-apnea-syndromes medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 333 clinical trials
K Konrad Bloch, Prof. Dr.

HighCycle Study: Effect of Acetazolamide on Sleep Disordered Breathing in Women Compared to Men

Randomized clinical trial evaluating the effect of acetazolamide on sleep disordered breathing in women compared to men travelling to 3600 m.

18 - 44 years of age All Phase 4
A Ambrose A Chiang, MD

Belun Ring Platform With an Improved Algorithm for OSA Assessment

OSA is commonly diagnosed with either attended in-lab polysomnography (PSG) or unattended home sleep apnea testing (HSAT). The BLS-100 (Belun Technology Company Limited, Hong Kong) is a novel neural network-based HSAT platform consists of a ring shape pulse oximeter sensor, a cradle, and an improved proprietary analytic algorithm. This study …

18 - 80 years of age All Phase N/A
C Chi-Hang Lee, MD

CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial

Obstructive sleep apnea (OSA) is a prevalent condition that significantly impacts the sleep health and overall well-being of millions of adults worldwide. It is characterized by breathing difficulties during sleep caused by an obstructed upper airway, leading to fragmented sleep, oxygen deprivation, and increased sympathetic activity. OSA and its associated …

45 years of age All Phase N/A
S Sanjay Patel, MD

OurSleepKit to Support CPAP Adherence

The goal of this clinical trial is to learn if a couple-focused mobile health intervention will improve the use of continuous positive airway pressure (CPAP), the primary treatment option for obstructive sleep apnea (OSA). Participants include newly diagnosed patients with OSA who are candidates for CPAP treatment and their partners. …

18 years of age All Phase N/A
P Pamela DeYoung, RPSGT

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?

Obstructive sleep apnea (OSA) is common in older adults and has recently been implicated in pathogenesis of Alzheimer's disease (AD). Research has shown that sleep disruptions have caused memory impairment. Sleep apnea is a form of sleep disruption. We would like to examine how obstructive sleep apnea may contribute to …

65 - 85 years of age All Phase 1
P Pamela DeYoung, RPSGT

Do Endotypes Predict Response and Sequelae in OSA Patients

This study will investigate why some people have Obstructive Sleep Apnea (OSA) and how the underlying cause may relate to OSA manifestations (including sleepiness and high blood pressure) and response to different therapeutic approaches (ie CPAP, eszopiclone, and supplemental oxygen). Understanding why someone has OSA could affect how best to …

21 - 65 years of age All Phase 2
E Enoch Ng, DDS

Photobiomodulation for Pediatric Hypertrophic Tonsils

Pediatric obstructive sleep apnea is a medical condition where a child has great difficulty with breathing, or stops breathing all together, while asleep. This is a medical condition for which the primary treatment is usually a surgery targeted towards removing swollen tonsils and adenoids. However, surgical removal of tonsils and …

6 - 12 years of age All Phase N/A
R Raf De Jongh, M.D.

Validation of the Smart Mask V1 System and Its Measurements of SpO2 and Pulse Rate

The goal of this clinical study is to investigate a new medical device, the Smart Mask V1 System (herein 'Smart Mask'), and particularly its measurements of blood oxygen levels (SpO2) and pulse rate (PR) in healthy adults aged 18 to 65. More specifically, the study is directed at answering the …

18 - 65 years of age All Phase N/A
L Lauren Melcher

Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome

This is an open-label study of the combination of atomoxetine and oxybutynin (ato-oxy) in children with Down syndrome and obstructive sleep apnea (OSA) documented by polysomnography (PSG). Participants will receive ato-oxy for 6 months. Ato-oxy dose will be 5 mg oxybutynin and 0.5mg/kg/day (max 40 mg) atomoxetine. Dosing of the …

6 - 17 years of age All Phase 2
W Winnie Chauvel, BS

PAP for Children With DS and OSAS

Determine the efficacy of family-informed intervention (INT) vs standard clinical care over a period of twelve months in children with obstructive sleep apnea and Down Syndrome.

6 - 18 years of age All Phase N/A

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