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sleep-apnea-syndromes Clinical Trials

A listing of sleep-apnea-syndromes medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 326 clinical trials
P Pedro R Genta, MD

Effect of Eszopiclone on Adherence to CPAP and Severity of Insomnia in Patients With COMISA

The comorbidity between obstructive sleep apnea (OSA) and insomnia (COMISA) is common, and associated with poorer sleep quality. CPAP adherence among COMISA patients is worst than among those with OSA only. The investigators will compare the effect of Eszopiclone 3mg or placebo for 14 days on adherence to CPAP after …

18 - 75 years of age All Phase 4
M Millene Camilo, MD, PhD

Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke

The study aims to evaluate whether early treatment of obstructive sleep apnea with continuous positive airway pressure in ischemic stroke patients has a favorable effect on functional recovery.

18 - 80 years of age All Phase N/A
E Eleni O'Neill

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils

The purpose of this study is to compare the effectiveness of a novel personalized surgical approach to the standard AT in children with small tonsils (ST). This will be accomplished by randomizing children with ST and OSA to one of these two treatments and comparing outcomes after 6 months. It …

2 - 17 years of age All Phase N/A
S Santos, MD

Neurostimulation for Sleep Disordered Breathing

This is a first in human study to determine if the Lunair Alpha System is safe and effective for treating moderate to severe sleep disordered breathing.

18 years of age All Phase N/A
Q Quintrele Jones, MPH

Atrial Fibrosis Progression in Sleep Apnea Patients: A Pilot Study

The investigators hypothesize that Obstructive Sleep Apnea (OSA) is an independent risk factor for atrial fibrosis development. The investigators aim to prove the presence and progression of atrial fibrosis on Delayed Enhancement Magnetic Resonance Imaging (DE-MRI) in OSA patients without atrial fibrillation (AF). The investigators will also investigate the correlation …

18 - 75 years of age All Phase N/A
C Chang Dae Lee, PhD

Smart Pillows for Enhancing Sleep Quality

The purpose of this study is to examine the impact of smart pillows on the sleep quality of individuals who experience a snoring issue and/or obstructive sleep apnea (OSA), as well as their sleep partners. Furthermore, this study will explore whether enhancements in sleep quality positively influence depressive symptoms, physical …

50 years of age All Phase N/A
L Lien Desteghe, MSc PhD

Structured Testing and Treatment for Obstructive Sleep Apnea in Patients With Atrial Fibrillation

The main goal of this prospective pre-post implementation study is to investigate how a structured testing and treatment program for obstructive sleep apnea using the NOX T3s device and a Fitbit smartwatch with the FibriCheck algorithm impacts the proportion of atrial fibrillation (AF) in an AF population. Participants will wear …

18 years of age All Phase N/A
J Jesus Lopez

Cardiometabolic Risk Effects of Short-term Cessation of Neurostimulation Therapy

Hypoglossal nerve stimulation (HGNS) is an implantable therapy that treats obstructive sleep apnea. The study will evaluate the effect of this treatment on cardiovascular and metabolism-related measures to see if it affects patients' risk of medical problems associated with obstructive sleep apnea (OSA).

18 years of age All Phase N/A
R Ruchi Rastogi, MSc

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

Cognitive dysfunction in the aging Veteran population is a growing health concern in the Veterans Health System. It is not known whether OSA coexisting with COPD will enhance the risk for cognitive dysfunction. The investigators sought to investigate whether these two highly prevalent diseases, that often co-exist as the 'Overlap …

60 - 89 years of age All Phase N/A
O Omar M Mohamed, Master

High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild to Moderate Obstructive Sleep Apnea

This study aims to compare the effectiveness of conventional oxygen therapy oxygen and high-flow nasal cannula therapy on oxygen saturation (SpO2), measuring number of SpO2 drop >4% of base line oxygen saturation (o2 desaturation index), length of the ICU stay, and the need of use supplemental continuous positive airway pressure …

21 - 40 years of age All Phase N/A

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