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functional-dyspepsia Clinical Trials

A listing of functional-dyspepsia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 40 clinical trials
H Helen Burton Murray, PhD

Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia

Randomized controlled trial of an exposure-based behavioral treatment (CBT) in adults with functional dyspepsia who meet criteria for avoidant/restrictive food intake disorder (ARFID) with weight loss.

18 years of age All Phase N/A
J Jemima Clarke

Traditional Dietary Advice Versus Low FODMAP Diet in Postprandial Functional Dyspepsia

Functional dyspepsia is common, affecting 7.2% of the global population, and associated with substantial health impairment. Almost 80% of patients with functional dyspepsia report meal-related symptoms and are classified as having the postprandial distress syndrome (PDS) variant. However, studies evaluating dietary modifications in PDS are sparse. The investigators will perform …

18 - 60 years of age All Phase N/A
S Sang Yeoup Lee, Professor, MD, PhD

Meu-cinn for Gastric Mucosal Health in Adults With Functional Dyspepsia

This clinical trial aims to determine whether Meu-cinn promotes gastric mucosal health in adults with functional dyspepsia and to assess its safety. The main questions are: Does Meu-cinn promote gastric mucosal health in participants? What side effects occur when participants take Meu-cinn?

19 - 70 years of age All Phase N/A

Efficacy of Clostridium Butyricum in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia

Objective: This study aims to evaluate the effectiveness of Clostridium butyricum in improving anxiety and depression in patients diagnosed with functional dyspepsia according to the Rome IV criteria. Methods: This trial plans to enroll 180 patients (90 per group). The study will employ a double-blind design. For patients diagnosed with …

18 - 80 years of age All Phase 4

Efficacy of Bacillus Coagulans in Alleviating Anxiety and Depression in Patients With Functional Dyspepsia

Objective: This study aims to evaluate the effectiveness of Bacillus coagulans in improving anxiety and depression in patients diagnosed with functional dyspepsia according to the Rome IV criteria. Methods: This trial plans to enroll 180 patients (90 per group). The study will employ a double-blind design. For patients diagnosed with …

18 - 80 years of age All Phase 4
Y Yanglin Pan, MD

Effects of Cognitive Behavioral Therapy Through a Mobile App on Patients With Refractory Functional Dyspepsia

Functional dyspepsia (FD) is a common gastrointestinal disease, which is associated with decreased life quality and increased medical cost. Antipsychotic drugs were demonstrated to be effective in relieving symptoms in FD patients, especially for patients with refractory FD. However, the use of those drugs was associated with obvious adverse events. …

18 - 80 years of age All Phase N/A
N Nashrulhaq Tagiling, MSc

Elucidating Mechanisms That Underlie the Symptomatology of Functional Dyspepsia Using Novel Techniques and Its Therapeutic Validation Using Neuromodulators

The goal of this study is to investigate the mechanisms of impaired gastric accommodation and emptying, dysfunctional duodenum, and micro-inflammation using novel imaging techniques of SPECT/CT, gastric emptying scintigraphy, MRI, high-resolution manometry, and inflammatory biomarkers, as well as to validate these mechanisms using a therapeutic trial of neuromodulator (mirtazapine) in …

18 - 65 years of age All Phase 1
X Xiaojing Wang

Correlation Study of Atrophic Gastritis and Dyspepsia Symptoms

Background Dyspepsia is a common gastrointestinal complaint globally, affecting approximately 21.8% of the population. Among patients presenting with dyspeptic symptoms, over 80% are diagnosed with functional dyspepsia (FD), while approximately 16% are found to have chronic atrophic gastritis (CAG). CAG represents an important precancerous condition in the gastric cancer cascade, …

18 - 75 years of age All Phase N/A
M M.M. Tabbers, Dr. PhD.

VICO-trial: Video Consultations in the Follow-up of Children With Functional Abdominal Pain Disorders

The goal of this non-inferiority randomized controlled multi-center trial is to investigate the use of video consultations in the follow-up care of children aged 4 - 18 years old with functional abdominal pain disorders (FAPDs). Video consultations will be compared to face-to-face consultations. Clinical outcomes and patients' and parents' healthcare …

4 - 17 years of age All Phase N/A
T Tea Soini, MD PhD

Pain in Pediatric Patients - Internet Interventions for Disorders of Gut-brain Interaction

Many children and adolescents often experience long-lasting stomach pain. In many cases, this is due to disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS), functional abdominal pain, and functional dyspepsia. These conditions are caused by disrupted communication between the brain and the gut. They are linked to …

8 - 17 years of age All Phase N/A

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