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functional-dyspepsia Clinical Trials

A listing of functional-dyspepsia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 40 clinical trials

A Phase III Trial of Z-338 in Paediatric Patients With Functional Dyspepsia

The purpose of this study is to evaluate pharmacokinetics, efficacy and safety of Z-338 of pediatric patients with functional dyspepsia (FD). In Part 1, the pharmacokinetics and safety of single oral dose of Z-338 100 mg are evaluated. In Part 2, the efficacy and safety of Z-338 100 mg orally …

9 - 17 years of age All Phase 3
M Maria Anastasia Darmawan, MD

Press Needle on Body Acupuncture Points and Auricular Acupuncture Points on Functional Dyspepsia

The aim of this study was to prove that press needle (PN) and medication are more effective in reducing symptoms and improving quality of life in people with functional dyspepsia compared to sham press needle (Sham PN) and medication. The main questions this study aims to answer are: Does the …

18 - 59 years of age All Phase N/A
K Karen Lin

Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Cognitive Behavioral Therapy in Functional Dyspepsia

The primary aims of this randomized, single-blinded, 2x2 sham-controlled trial are to 1) evaluate synergistic impact of 8-weeks of transcutaneous auricular vagus nerve stimulation (taVNS) + cognitive-behavioral therapy (CBT) on post-meal gut-brain communication; 2) determine the sequential relationship between treatment-associated changes in gastrointestinal-related anxiety and both clinical functional dyspepsia (FD) …

18 - 65 years of age All Phase N/A
G Gerard DASSA, DR

Probiotic and Ginger Supplement for Symptoms and Quality of Life in Functional Dyspepsia (SUBTILE)

Functional dyspepsia (FD) is a frequent functional gastrointestinal disorder characterized by bothersome postprandial fullness, early satiety, epigastric pain, or burning, in the absence of any structural or metabolic cause. It significantly impairs quality of life and has limited therapeutic options, as conventional treatments such as proton pump inhibitors often show …

18 years of age All Phase N/A
J Jan Tack, PhD, MD

The Six Food Elimination in Postprandial Distress Syndrome

The six food elimination diet, as known in eosinophilic esophagitis, will be performed in 15 patients with functional dyspepsia (subtype postprandial distress syndrome). Screening will exclude patients with allergies by performing immunocaps on blood. Before and after the 8 weeks of diet, an gastroduodenoscopy with biopsies will be performed to …

18 - 70 years of age All Phase N/A
J Jan Tack, PhD, MD

PEA in Functional Dyspepsia

The goal of this placebo controlled randomized double blind interventional study is to assess the effect of palmitoylethanolamide supplementation in patients with functional dyspepsia The main questions it aims to answer are: The efficacy of PEA on functional dyspepsia symptoms measured using the LPDS questionnaire The effect of PEA on …

18 - 70 years of age All Phase N/A
A Andy Bolender

Vagal Nerve Stimulation for Functional Dyspepsia and Gastroparesis

Explore the effects of auricular transcutaneous vagal nerve stimulation (taVNS) on brain and stomach outcomes in functional dyspepsia and gastroparesis patients.

18 - 70 years of age All Phase N/A
R Raika Jamali

Evaluating the Efficacy of "Digestive Aid" in Functional Dyspepsia

Functional Dyspepsia (FD) is diagnosed in the presence of bothersome epigastric pain or burning, early satiation and/or postprandial fullness of greater than 8 weeks duration, in the absence of alarm signs. Alarm signs include weight loss, gastrointestinal bleeding, anemia, dysphagia, and family history of upper gastrointestinal malignancies. FD is a …

18 - 75 years of age All Phase N/A
J Jemima Clarke

Traditional Dietary Advice Versus Reassurance-alone in Postprandial Functional Dyspepsia

Functional dyspepsia is common, affecting 7.2% of the global population, and associated with substantial health impairment. Almost 80% of patients with functional dyspepsia report meal-related symptoms and are classified as having the postprandial distress syndrome (PDS) variant. However, studies evaluating dietary modifications in PDS are sparse. The investigators will perform …

18 - 60 years of age All Phase N/A
E Elizabeth Meyer, MPH

Brain-Gut Yoga for Functional Dyspepsia and Gastroparesis (FD-GP)

The purpose of this research study is to assess whether using a yoga-based intervention in practice is feasible (possible) and acceptable to patients with Functional Dyspepsia and/or Gastroparesis (FD-GP).

18 years of age All Phase N/A

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