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kidney-transplantation Clinical Trials

A listing of kidney-transplantation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 191 clinical trials
V Vincent Audard

BIOmarkers Before and After Kidney Transplantation

In clinical nephrology, the search for urinary, blood and tissue biomarkers of specific kidney diseases is an important goal. In recent years, the use of these biomarkers has made it possible to diagnose many renal diseases that affect the native kidney. In some cases, biomarkers may be useful in determining …

18 years of age All Phase N/A
A Andrew Malone

Trifecta-Kidney cfDNA-MMDx Study

Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood, and the Molecular Microscope® (MMDx) Diagnostic System results in indication biopsies.

years of age All Phase N/A
J Jae Berm Park, MD

Tacrolimus Exposure in Kidney Transplantation

Using CDW data from 5 tertiary hospitals in Korea, this study identify the optimal range of trough level that can prevent adverse outcome in the early periods after transplantation.

years of age All Phase N/A
M Maarten Naesens, MD, PhD

BIOBANK Renal Transplantation University Hospitals Leuven

This study aims to maintain a prospective biobank of human samples obtained from donors and recipients of renal allografts, including biopsy tissue, peripheral blood samples and urine samples.

years of age All Phase N/A
H Hana Vankova, MD, PhD

Comprehensive Geriatric Assessment in Kidney Transplantation

This observational study aims to analyze the results of comprehensive geriatric assessment and to monitor the development of functional status in geriatric kidney transplant candidates and recipients.

60 years of age All Phase N/A
J Jairo Chavez, BA

Proteogenomic Monitoring and Assessment of Kidney Transplant Recipients

Chronic Allograft Nephropathy (CAN)/Interstitial fibrosis and Tubular Atrophy (IFTA) is responsible for most kidney transplant failures. CAN/IFTA on a 3 month kidney biopsy strongly predicts graft survival long term. CAN/IFTA remains a vexing problem for clinicians because current monitoring tools, namely the serum creatinine concentration, are not sensitive to early …

18 years of age All Phase N/A
L Lynnette Moats

APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

The APOLLO study is being done in an attempt to improve outcomes after kidney transplantation and to improve the safety of living kidney donation based upon variation in the apolipoprotein L1 gene (APOL1). Genes control what is inherited from a family, such as eye color or blood type. Variation in …

years of age All Phase N/A
M Martin Tepel, Dr

Molecular Biological and Moleculargenetic Monitoring of Therapy After Kidney Transplantation

Molecular monitoring is conducted in blood cells, plasma samples, urine samples and/or tissue from patients after kidney transplantation. In the present study the investigators examine the hypothesis that noninvasive diagnostic molecular monitoring can improve the outcome after transplantation. Routine clinical and laboratory data from serum and urine are evaluated at …

18 years of age All Phase N/A
A Alicja Dębska-Ślizień, Professor

Tacrolimus and Risk Factors for Glucose Metabolism Disorders in Kidney Transplant Patients

Many people who receive a kidney transplant develop problems with how their body processes sugar (glucose). This includes conditions like prediabetes and diabetes, which can lead to more health issues, such as heart problems and infections. One of the main medications used after a kidney transplant, called tacrolimus, can contribute …

18 years of age All Phase N/A
D Dominique Bertrand, MD

Alloreactive Memory B Lymphocytes and Anti-HLA Sensitization

In transplantation, B lymphocytes are major cellular players in the alloreactive humoral response through the production of antibodies targeting allogeneic HLA molecules expressed by the transplant. In subjects sensitized to HLA antigens, the contribution of pre-existing alloreactive memory B lymphocytes (Bmem) to allograft rejection phenomena after transplantation is now recognized. …

18 years of age All Phase N/A

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