Overview
Using CDW data from 5 tertiary hospitals in Korea, this study identify the optimal range of trough level that can prevent adverse outcome in the early periods after transplantation.
Eligibility
Inclusion Criteria:
- Renal transplant recipients between January 1, 2005 through December 31, 2014 in one of the five participating centers
- Patients receiving oral tacrolimus as one of the main immunosuppressant at the start of the defined cohort time (i.e. at post-transplant 2 months for the analysis of 1-year outcomes and at post-transplant 12 months for the analysis of 6-year outcomes)
Exclusion Criteria:
- Graft failure occurring within the first 2 month of transplantation
- Mortality of any cause occurring within the first 2 month of transplantation
- Patients moving centers during the study period
- Patients who have received other organ transplantation(s) besides renal transplantation in the defined period