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appendicitis Clinical Trials

A listing of appendicitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 27 clinical trials

Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy

This study is designed as a randomized controlled trial with patients assigned to neuromuscular reversal with either sugammadex or neostigmine/glycopyrrolate reversal. The study will not be blinded to the anesthesiologist to allow for appropriate decision-making on timing and dosage of reversal. This is a single-center study.

2 - 17 years of age Both Phase 4
M Mustafa Azizoğlu

Transumbilical Laparoscopic Appendectomy

Transumbilical laparoscopic appendectomy (TULA) is increasingly favored in the treatment of appendicitis within the realm of minimally invasive surgical approaches. This procedure offers advantages such as superior cosmetic outcomes and reduced postoperative pain. However, like all surgical interventions, it carries the inherent risk of surgical site infections (SSI), which pose …

5 - 18 years of age Both Phase N/A

Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis

This will be an explorative, proof-of-principle, open, multi-center investigation. The investigation aims to investigate the safety of the PERIsign system and the ability of physicians to differentiate between healthy individuals and subjects with involuntary muscle defense as a sign of peritonitis by utilizing PERIsign data. The investigation will include a …

18 - 70 years of age Both Phase N/A
M Mohamed Eltorki, MBChB, MSc

Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain

Appendicitis is a common condition in children 6-17 years of age, and the top reason for emergency surgery in Canada. Children with appendicitis can have very bad pain in their belly. Children often need pain medications given to them through a needle in their arm called an intravenous (IV). The …

6 - 17 years of age Both Phase 3
C Carlos Leganes, MD

Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics

Evaluate the application of the new therapeutic model post Fast Track surgery, in complicated acute appendicitis, in pediatric population on the rate of complications postoperative in the form of abdominal abscesses.

2 - 16 years of age Both Phase 4
A Amélie JURINE, Doctor

TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children

When performing laparoscopic appendectomy in children, regional anesthetic techniques are rou-tinely used concomitantly with general anesthesia. These techniques include local infiltration of the trocar wounds or transverse abdominal plane block (TAP block). In 2018, a position paper of the European Society of Pediatric Anaesthesiology advised for TAP block over local …

3 - 15 years of age Both Phase N/A
M Mohamed Eltorki, MD

Comparison of Ketorolac at Three Doses in Children With Acute Pain

Hospital Scene #1: A 6-year-old arrives in the Emergency Department at McMaster Children's Hospital (MCH) complaining of pain in his lower right side. His Dad explains the pain has been going on for a few hours and that Advil and Tyelnol haven't helped at all. He's anxious and concerned about …

6 - 17 years of age Both Phase 3

New Diagnostic Markers In Dignosis Of Complicated Appendix

Most common cause of acute abdomen is acute appendicitis delay dignosis of acute appendicitis lead to complications as perforation this study examined efficacy of hyperbilirubinemia&hyponatremia as indicator of complicated appendicitis

10 - 40 years of age Both Phase N/A
C Chao Han, M.D.

A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis

The incidence of PD is high, and when the disease is serious to a certain extent, the effect of drugs to control symptoms decreases, resulting in a significant reduction in the quality of life of patients. Recent studies have found that these PD symptoms are closely related to the intestine. …

40 - 70 years of age Both Phase N/A
K Kaitlyn Infante

Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX) - Atrium Health

To demonstrate the safety, efficacy, and feasibility of short-course post-operative antibiotic treatment for simple and complicated appendicitis

18 - 100 years of age Both Phase N/A

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