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thyroid-disorders Clinical Trials

A listing of thyroid-disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 294 clinical trials
S Susana LEONARD, CRA

Pilot Study for Thyroid Surgery by Preoperative Video Support and Personalized and Secure Web Platform

The medical information delivered to the patient before any surgery constitutes an essential and compulsory step during the initial management of the operated patient. There are different reasons for the quantity and quality of medical information retained by the patient. An internet platform with personalized and secure access has been …

18 - 75 years of age All Phase N/A
K Klaas Van Den Heede, MD

Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Thyroidectomy

Hypoparathyroidism (and the resulting hypocalcemia) remains the most common morbidity after a total thyroidectomy. The identification and preservation of parathyroid glands during neck surgery has always been challenging but is crucial to avoid postoperative hypocalcemia. Recently, the specific autofluorescent characteristics of endogenous fluorophores in the parathyroid tissue have been used …

18 years of age All Phase 3
F Fabio Capelli, phd

Transoral Endoscopic Thyroidectomy by Vestibular Approach (TOETVA)

Prospective study carried out with ICESP (instituto do Câncer do Estado de São Paulo) patients with thyroid disease with surgical indication

18 - 70 years of age All Phase N/A
S Solveig Konst, Cand.Med

Patient-centered Dosage of Levothyroxine

Levothyroxine is the most used thyroid hormone replacement when the thyroid gland is failing. Because dosage adjustment normally takes several months, the investigators have developed a decision support tool (DST) that predicts optimal dosage based on repeated blood samples the first 2 weeks after initiation of therapy. In this randomized …

18 years of age All Phase N/A
J Jianyong Lei, MD

A Study of Online Follow-up in Patients With Papillary Thyroid Cancer

The randomized, actively controlled, non-inferiority trial is scheduled to begin in August 2024 and run through August 2026. Inclusion criteria: (1) has undergone microwave ablation of thyroid or thyroidectomy (including endoscopy and opening) at the Department of Thyroid Surgery of West China Hospital of Sichuan University, (2) is between 18 …

18 - 90 years of age All Phase N/A
G Gabor Szinnai, Prof. MD, PhD

Prospective Evaluation of OptiThyDose

The aim of this multicentric, randomised, two-arms and single-blinded clinical trial is to prospectively evaluate OptiThyDose for Congenital hypothyroidism (CH) and Graves' disease (GD).

- 18 years of age All Phase N/A
N Nagy malak

Analgesic Efficacy of an Intermediate CPB in Neck Surgeries.

This study aims to investigate the analgesic efficacy of Intermediate Cervical Plexus Block combined with GA using two bupivacaine concentrations in patients undergoing neck surgeries (total thyroidectomy or total laryngectomy)

40 - 70 years of age All Phase N/A

Treatment of ARDS With Instilled T3

It is hypothesized that instillation of Liothyronine Sodium (T3) into the airspace will be safe, well tolerated, and will increase alveolar fluid clearance and decrease inflammation in patients with ARDS, reflected in improved oxygenation index (OI) and oxygenation saturation index (OSI).

18 years of age All Phase 2

Dosing of LT4 in Older Individuals

Our overall goal is to determine the clinical consequences of allowing greater flexibility in LT4 dosing in older individuals who take LT4.

65 years of age All Phase 4
K Kalaipriya Gunasekaran, MD

Interventional Study to Improve Medication Adherence Using Patient Decision Aid

Background Although hypothyroidism is easily treated with levothyroxine (LT4) replacement, results from several studies indicate that people receiving LT4 replacement often have under- or over-replaced thyroid function. Poor medication adherence and factors interfering with thyroxine absorption and bioavailability may result in such under-replacement. Using the COM-B (Capability, Motivation, and Opportunity …

21 years of age All Phase N/A

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