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thyroid-disorders Clinical Trials

A listing of thyroid-disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 295 clinical trials
Y Yu Feng

Huaxi Tunnel Technique For Recurrent Laryngeal Nerve Exposure And Dissection In Thyroid Surgery

Protection of the recurrent laryngeal nerve (RLN) is a key focus and difficulty in thyroid surgery. Unilateral RLN injury can lead to ipsilateral vocal cord paralysis, resulting in hoarseness in patients postoperatively. Bilateral RLN injury, however, may cause bilateral vocal cord paralysis, leading to dyspnea and even asphyxiation; in severe …

18 - 75 years of age All Phase 3
J Jingliang Ruan, PhD

Preoperative Prediction of Lymph Node Metastasis in T1N0M0 Papillary Thyroid Carcinoma by Using Contrast-enhanced Ultrasound

Similarly, the burden of central lymph node metastasis affects the individualized management of patients with T1N0M0 papillary thyroid carcinoma (PTC): lymph node metastasis is a contraindication to thermal ablation; low-burden lymph node metastasis is suitable for lobectomy; and high-burden lymph node metastasis recommends total thyroidectomy. However, conventional preoperative imaging examinations …

years of age All Phase N/A
P Peiliang Lin, M.D.

Comparative Study of Transaxillary Robotic Thyroidectomy With MRND Versus Conventional Open Surgery in N1b PTC

Thyroid cancer is one of the most common malignant tumors in women, ranking seventh in the United States and fourth in China. Papillary thyroid carcinoma is the most common pathological type (about 85% to 90% of thyroid cancers), and lateral cervical lymph node metastasis can reach 0.6-37.5% at diagnosis. For …

18 - 70 years of age All Phase N/A

A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease

Phase 2b trial of TOUR006 in Thyroid Eye Disease (TED) to evaluate 20mg and 50mg doses against placebo given by a subcutaneous injection every eight weeks to TED patients who are in the active inflammatory phase of disease.

18 - 80 years of age All Phase 2

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

To assess: efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET amplification, solid tumors harboring MET fusion, primary CNS tumors harboring MET alterations, solid tumors harboring wild-type MET with overexpression of HGF and MET efficacy …

18 years of age All Phase 2

Personalized Treatment in Thyroid Disorders

The Collar Therapy Indicator (CoTI) (A device that is placed in collar around the neck resembling a turtle neck sweater collar with a wire and recording box) has been shown in a single small previously published experience to provide data regarding radioiodine exposure that correlates with conventional methods of measuring …

21 - 65 years of age All Phase N/A

Preoperative Corticosteroids in Autoimmune Thyroid Disease

This study proposes to randomize patients about to undergo surgery for their autoimmune, inflammatory thyroid disease, and determine if a short course of corticosteroids decreases the inflammation of the gland and makes surgery less difficult.

18 years of age All Phase 4

Methods of Post Operative Analgesia in Patients Undergoing Thyroidectomy

this study aims to compare between effects of lidocaine and ketamine infusion on postoperative analgesia in patients undergoing thyroidectomy.

18 - 75 years of age All Phase N/A

Impact Of Thyroid Dysfunction on Liver Function Tests

This study aims to evaluate the effect of thyroid dysfunction on liver function tests.

20 - 60 years of age All Phase N/A
T Tao Luo

The Effective Blood Concentration of Ciprofol

Eligible patients were selected and enrolled in the study. General anesthesia was induced using ciprofol in all participants, with standardized evaluation of consciousness levels during induction. The patients' pain and cognition are followed up after surgery.

18 - 65 years of age All Phase N/A

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