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liver-disorders Clinical Trials

A listing of liver-disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,510 clinical trials
M Marianna Maspero

Liver Transplantation for Unresectable Intrahepatic Colangiocarcinoma After Sustained Response to Neoadjuvant Treatments

This is single-arm, observational, academic, investigator-driven study investigating the efficacy of liver transplantation after successful and sustained downstaging/tumor control of liver-limited unresectable intrahepatic cholangiocarcinoma. The downstaging protocol includes chemotherapy +/- immunotherapy and transarterial radioembolization (TARE) with Yttrium-90 in various combinations.

18 - 70 years of age All Phase N/A

Role of Photon Counting CT in Detecting Liver Metastatis From Colorectal Cancer

Colorectal cancer is the first leading cause of cancer death in men and second in women. Its incidence rates also increased by 1%-2% annually in young adults (ages <55 years). The liver is the most common site of colorectal cancer metastasis, with approximately 25% 50% of patients developing liver metastases …

18 - 100 years of age All Phase N/A
C Chunling Jiang, PhD

Evaluation of Pulmonary Complications in Liver Transplantation Patients Based on Machine Learning

The main objective of this study is to develop a machine learning model that predicts moderate-severe prediction model of pulmonary complications in liver transplantation patients within 14 postoperative day using a real-world, local preoperative and intraoperative electronic health records, not administrative codes.

18 - 80 years of age All Phase N/A
Y Yu-Chen Fan

Single Cell Landscape of HBV-related Acute-on-chronic Liver Failure Patients

This study aimed to profile the peripheral blood immune cells of patients with HBV related acute-on-chronic liver failure using single-cell RNA sequencing to reveal the immunopathological mechanisms of HBV related acute-on-chronic liver failure.

18 years of age All Phase N/A
M Mario Mondelli, MD

Collection of Blood and Tissue Samples From Patients With Primary Liver Cancer.

The project aims to collect blood, tissue samples, and clinical data from patients with primary liver cancer (mainly hepatocellular carcinoma and intrahepatic cholangiocarcinoma) undergoing systemic therapy, surgical resection, or liver biopsy. Primary liver cancer is a growing global health challenge, with over one million cases expected by 2025 and a …

18 - 90 years of age All Phase N/A
F Falk Roeder, MD

Prospective Observational Trial to Evaluate Quality of Life After Stereotactic Ablative Radiation Therapy in Patients With Hepatocellular Carcinoma

Prospective single arm, single center observational study to evaluate Quality of Life (Qol) after stereotactic body radiotherapy for patients with hepatocellular cancer. Patients will receive work-up, treatment and follow-up exclusively as routinely done except additional quality of life measurements. Qol will be measured by standardized and validated EORTC questionaires at …

18 years of age All Phase N/A

Incidence and Predictors of Post-TIPS Heart Failure in Patients With Cirrhosis

The purpose of this study is to conduct a prospective trial to investigate the incidence of heart failure in cirrhosis patients undergoing transjugular intrahepatic portosystemic shunt ,and to analyze the the predictors and modififications of cardiac function.

18 - 75 years of age All Phase N/A
D Dr. Madhumita Premkumar, MD

Clinical Diagnosis and Pathological Spectrum of Porto-sinusoidal Vascular Disease in India

There is a need to re-evaluate the patients classified as NCPH and determine whether the new histological classification proposed by the VALDIG applies to the Indian scenario. We intend to identify the patient cohorts who have been diagnosed as NCPH, NCPF, EHPVO, hepatic venous outlet tract obstruction (HVOTO), Veno-occlusive disease …

12 - 70 years of age All Phase N/A
M Mihai L Ciocirlan

Predictive Values of Presepsin Levels in ASciteS in Patients With Chronic Liver Failure

The investigators aim to study the predictive value of presepsin in ascites in newly admitted patients with chronic liver failure.

18 years of age All Phase N/A
S Sara Ali Sedeek, M.D.

Risk Factors and Outcome of Biliary Complications Following Adult Living Donor Liver Transplantation

Liver transplantation (LT) is a live-saving therapy for patients with complicated chronic liver diseases and acute liver failure .Even though many complications can occur after LT, biliary complications (BC) are both common and potentially severe . a prospective study and retrospective part from hospital records. Aim of the study: Detect …

18 - 65 years of age All Phase N/A

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