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liver-disorders Clinical Trials

A listing of liver-disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,510 clinical trials

Simultaneous Prospective Kidney Transplant Assessment in Combined Liver Kidney Candidates

The purpose of the study is to determine how much a persons kidney function recovers after receiving a simultaneous liver kidney transplant. The investigators will be contacting patients with kidney dysfunction with estimated GFR between 25 and 40 (not on dialysis treatment) who are listed to receive a simultaneous liver …

18 years of age All Phase N/A

Cera™ Vascular Plug System Post-Market Clinical Follow-Up

The objective of the study is to collect and evaluate clinical data on patients of the Lifetech Cera™ Vascular Plug System to: confirm the performance confirm the safety identify previously unknown side-effects monitor the identified side-effects (related to the procedures or to the medical devices) identify and analyse emergent risks

18 - 85 years of age All Phase N/A
A Alan L Hutchison, MD, PhD

Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant

The goal of this observational study is to establish risk factors for post-transplant in adult individuals with cirrhosis without diabetes undergoing liver transplant evaluation. The question being addressed is: can laboratory work, anthropometric tests, functional tests, imaging, and advanced measurements such as wrist actigraphy, continuous glucose monitoring, or oral glucose …

18 - 75 years of age All Phase N/A

Analysis of Donor-derived Cell Free DNA in Liver Transplant Patients

Determine the levels of Donor-derived (dd)cell-free DNA(cfDNA )in liver transplant recipients with normal liver function tests (LFTs) indicating stable immunosuppression status (IS). Based on this range use the dd-cfDNA levels to determine over or under IS in liver transplant patients to make changes to their IS medication regimen.

18 years of age All Phase N/A

ctDNA in CRC Patients Undergoing Curative-intent Surgery for Liver Metastases

This is a prospective multicenter cohort study, was designed to explore the prognostic value of ctDNA as a biomarker of disease response and recurrence or death in patients undergoing curative-intent surgical resection of Colorectal cancer liver metastasis.

18 years of age All Phase N/A
N Nelson Barrera, PhD

Pharmaco-proteomic Platform to Evaluate Drug Interactions in Liver Transplant Patients

The goal of this observational study is to enhance the ability to forecast kidney failure in liver transplant patients in the ICU under multidrug treatment by developing a computer platform that integrates mathematical models of drug interactions, proteomics, and clinical data. The main outcomes it aims to develop are: Design …

18 years of age All Phase N/A
W Weilin Wang

Early-stage Detection of Liver Cancer by Proteins in Peripheral Blood

By collecting blood samples from liver cancer patients and healthy individuals, and comparing the blood protein profiles of the two, the biomarkers for early diagnosis and tissue traceability were identified to accurately establish an early diagnosis model for liver cancer and verify its efficacy.

18 - 75 years of age All Phase N/A
M Ming Yu, PhD, MD

Exploration of Noninvasive Differential Diagnosis of Benign and Malignant Liver Tumors

To explore an effective noninvasive method for differential diagnosis of liver tumors.

18 - 70 years of age All Phase N/A
S Study Coordinator

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

Liver transplantation (LT) has become an accepted treatment for selected patients with unresectable liver metastases due to colorectal cancer (CRLM). The goal of this study is to look at and compare the clinical results of all the different approved methods (living vs. Deceased, whole organ vs. Split, one staged vs. …

18 years of age All Phase N/A
V VIAUD JULIETTE, Dr

A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers

The aim of this French multicenter retrospective study is to describ rare primary hepatic cancers clinical, histological and radiological features, to obtain a biological tumor and blood collection, and to evaluate the efficacy of treatments received in clinical practice in order to determine optimal therapeutic sequences. This retrospective cohort will …

18 years of age All Phase N/A

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