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neoplasms Clinical Trials

A listing of neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,299 clinical trials
M Michiel Kroesen, MD, PhD

Thermoradiotherapy for Locally Advanced Head and Neck Cancer Patients

Patients with head and neck cancer treated with radiotherapy (RT) have a substantial change of recurrence of the tumor in the pharynx or lymph nodes in the neck. Once tumor and/or lymph nodes have recurred, the prognosis is poor. To increase the efficacy of RT, usually chemotherapy is added to …

18 years of age All Phase 1
M Mao-Lin Yan

mFOLFIRINOX Plus Anlotinib and Sintilimab for Advanced Pancreatic Cancer

This study is a prospective, single-arm, multicenter, phase Ib/II clinical trial that treats previously untreated patients with locally advanced or metastatic pancreatic cancer using mFOLFIRINOX in combination with anlotinib and sintilimab. The purpose of this trial is to evaluate the efficacy and safety of this treatment regimen and to preliminarily …

18 - 75 years of age All Phase 1/2
S Sarah Sunshine, MD

Ocular Complications From Cancer Therapy - Patient Registry and Biobank

The purpose of this study is to collect data on patients seen at University of Maryland after undergoing cancer therapy. Previous medications, ocular history, medical history, clinical evaluations, surgical procedures and outcomes will be gathered on the patients who consent to participate. Potential subjects will be enrolled from the clinical …

18 years of age All Phase N/A
S Shuk Ting Cheung, PhD

Acupressure on Xerostomia in Head and Neck Cancer Patients

This is a randomized controlled trial aimed to1) examine the effect of a self-administered acupressure intervention on head and neck cancer patients with xerostomia (primary outcome) relative to oral health education control; 2) examine the effect of self-administered acupressure on secondary outcomes, including quality of life and severity of symptoms …

18 years of age All Phase N/A
J Jean Toscano, PhD

Physical and Health Outcomes With ExeRcise in Cancer SURVIVORS

This study aims to evaluate the effect of a physical exercise intervention model on breast cancer survivors and their adherence. The sample will consist of 30 women with a primary diagnosis of breast cancer. The intervention will be carried out in a highly complex oncology center in Maceió-AL, Brazil, using …

18 - 90 years of age Female Phase N/A

Web-based Intervention for Long-term Breast Cancer Survivors

The number of breast cancer survivors is growing. More cured women are becoming long-term survivors of breast cancer (LS-BC) at least 5 years after diagnosis and after treatment has been completed. Some of these LS-BC return to daily life without any problems; however, in many cases, they experience and have …

18 - 99 years of age Female Phase N/A

Adding IL-2 to Tebentafusp to Eradicate Cancer Progression

A recent clinical trial found that after 36 months, patients taking tebentafusp had a median survival of 21.6 months, compared to 16.9 months for those in the control group. Since recruitment for tebentafusp in metastatic uveal melanoma (mUM) has ended, a new trial is starting to test whether adding IL-2 …

18 years of age All Phase 1/2
M Mara M Mara Mantiero, MD

Akynzeo as Antiemetic Treatment in Patients With Endometrial Cancer

The clinical trial concerns the use of an innovative "anti-emetic" drug (that is, anti-vomiting and nausea) in subjects affected by endometrial cancer. It is addressed to patients who have never received chemotherapy before and are about to start a treatment with platinum and taxanes with or without immunotherapy for endometrial …

18 years of age Female Phase 4
j jin yang

Induction Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

This is a Phase II clinical study for patients with locally advanced cervical cancer, aimed at evaluating the efficacy, safety, and tolerability of Cadonilimab combined with chemotherapy as induction therapy.

18 years of age Female Phase 2
J Jenna Gillen

Multiple Risk Factor Intervention Trial in Breast Cancer Survivors

This study aims to produce new evidence on the efficacy of exercise and diet for cardiometabolic risk reduction in BC survivors. Using a 3-arm RCT with to 6 months of 1) exercise following Health Canada guidelines; 2) the same exercise plus counselling to follow Canada's Dietary Guidelines to improve diet …

years of age Female Phase N/A

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