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neoplasms Clinical Trials

A listing of neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,299 clinical trials

Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment.

The POWER-study is a two-arm exercise intervention study for pediatric patients following acute cancer treatment. This clinical trial will investigate the effects of a 12-week moderate to high-intensity exercise program on cardiorespiratory fitness in children and adolescents beginning 6 weeks after completion of acute cancer treatment.

7 - 23 years of age All Phase 2/3
M MUSTAFA ALBAYRAK, MD

Sentinel Lymph Node Biopsy in Early-Stage Ovarian Cancer

The primary goal of this prospective study is to define the efficacy of the sentinel lymph node biopsy (SLNB) procedure by comparing it to the results obtained from systematic lymphadenectomy, each performed in participants with a suspicious adnexal mass for early-stage ovarian cancer.

18 - 90 years of age Female Phase N/A
S STEP-Together Coordinator

Sleep Treatment Education Program for Cancer Survivors: STEP-Together

This single-arm research study of off-treatment cancer survivors with self-reported symptoms of insomnia will test the Sleep Treatment Education Program Together (STEP-Together) intervention which is delivered as a synchronous group session by videoconference.

18 - 89 years of age All Phase N/A

A Study of JNJ-89402638 for Metastatic Colorectal Cancer

The purpose of this study is to determine the putative recommended phase 2 dose(s) (RP2Ds) of JNJ-89402638 and to determine the safety of JNJ-89402638 at the RP2D(s) in participants with metastatic colorectal cancer.

18 years of age All Phase 1
G Gardian Lukman Hakim, Anesthesiologist-Intensivist

Effect of Dexmedetomidine on Microsurgery Reconstruction in Cancer Patient

This double-blinded randomized controlled trial aims to investigate the effect of intraoperative dexmedetomidine administration on early flap viability and microvascular integrity in cancer patients undergoing elective microvascular reconstructive surgery. The primary outcome is clinical flap viability within 48 hours postoperatively, assessed using a standardized scoring system based on flap color, …

18 - 65 years of age All Phase N/A
Q Qin Xu

Nituzumab Plus Serplulimab Combined With SBRT in Cervical Cancer

In recurrent advanced cervical cancer, patients were prone to drug resistance who have relapsed within prior platinum-based chemotherapy. However, immune checkpoint inhibitor's combination therapy has become a promising strategy for advanced cervical cancer. Epidermal Growth Factor Receptor (EGFR) is overexpressed in cervical cancer cells. Stereotactic radiotherapy (SBRT) can enhance the …

18 - 75 years of age Female Phase 2
M Min Yan

Utidelone Capsule Plus Capecitabine (CAP) for Metastatic Breast Cancer

This study aims to investigate the efficacy and safety of utidelone capsule plus Capecitabine in the treatment of advanced breast cancer , and thus provides a new systemic treatment strategy for those patients. This study was a single-arm, phase II study of patients with recurrent or metastatic HER2-negative breast cancer …

18 - 70 years of age Female Phase 2
B Barry Wenig, MD

Perioperative Nutritional Optimization in Head and Neck Cancer Patients

To determine whether nutritional optimization in head and neck cancer patients undergoing major surgery will decrease post-operative wound complications. The Investigators hypothesize that nutritional supplementation with Nestle Impact Advanced Recovery (AR) will decrease the rate of wound complications after surgery

18 years of age All Phase N/A
X Xingwen Fan, Doctor

Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)

The goal of this clinical trial is to learn the role of adjuvant chemotherapy for patients with thymic carcinoma and completed resection. The main questions it aims to answer are: Does adjuvant chemotherapy decrease disease progression? Does medium dose of three drugs (paclitaxel, cisplatin, 5-FU) well tolerance? Researchers will compare …

18 - 75 years of age All Phase 3

Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer

The purpose of the study is to test a treatment strategy with currently approved drugs to see if it is practical to administer the available drugs in a new way that researchers hope could be more effective in treating metastatic breast cancer.

18 years of age Female Phase N/A

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