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constipation Clinical Trials

A listing of constipation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 90 clinical trials
C Carlette Villarreal

4-Week, Multi-center Dose-Ranging Study for the IBS-C in Pts. 6 to <12 Yrs

This is a randomized, double-blind, placebo-controlled dose-ranging study to assess the safety and efficacy of tenapanor for treatment of the IBS-C in pediatric patients 6 to less than 12 year old.

6 - 11 years of age All Phase 2

Effect of Pre-Surgery Constipation Podcast: A RCT

In this study, the investigators will evaluate the effect of a podcast on constipation on the number of patients with constipation. It is hypothesised that the podcast on constipation, will prevent constipation in the period leading up to and after surgery. This is a randomised controlled trial. The population of …

18 years of age All Phase N/A
s serhad bekir sünbül

Investigation of the Effect of Manual Therapy and Pelvic Floor Exercises on Pelvic Floor Muscles

The goal of this clinical trial is to Investigation of the effect of manual therapy and pelvic floor exercises on pelvic floor muscle in women with constipation. The main question[s] it aims to answer are: In addition to pelvic floor exercises, manual therapy applied to the pelvic floor muscles has …

18 - 55 years of age Female Phase N/A
R Ravinder K Mittal, MD

Defecation Patterns in Constipated Patients

Chronic constipation (CC) is a common condition that affects up to 25% of the population in North America. It poses a major burden on the healthcare cost. The pathophysiology of this condition is poorly understood and consequently there are inadequate treatments. Current diagnostic tests provide incomplete and often conflicting information. …

21 - 75 years of age All Phase N/A
Y Yaowen Hu

Effects of Lactulose on Gut Microbiota and Metabolism in Diabetic Constipated Patients

Constipation is the most common gastrointestinal manifestation in diabetic patients. Emerging evidence suggests that gut microbiota dysbiosis may contribute to the pathogenesis of diabetes, highlighting the need to investigate its role in diabetic constipation, though current research remains limited. Current management of diabetic constipation primarily relies on bulk-forming and osmotic …

18 - 70 years of age All Phase N/A
C Chin-Lin Hsu, Professor

Effects of Probiotics on Symptoms of Constipation in Adults With Functional Constipation

The purpose of this study was to evaluate the efficacy of 1 capsules of ABKefir per day on symptoms of constipation in subjects with functional constipation by clinical trial.

18 - 75 years of age All Phase N/A
E Erhan Kızmaz, PhD

Visceral Osteopathy in Functional Constipation

It is a functional bowel disease characterized by excessive straining during defecation, infrequent defecation, and the feeling of incomplete evacuation. There are very few studies investigating the incidence and prevalence of functional constipation.Non-pharmacological treatment methods, including lifestyle changes, are primarily recommended for the treatment of constipation. The aim of the …

18 years of age All Phase N/A
H Harichandana Punukula, PharmD, MS

Tenapanor in Synucleinopathy-Related Constipation

Investigation of tenapanor as a potential treatment for synucleinopathy-associated constipation

50 - 89 years of age All Phase 2
F Fan Zheng, MD

Efficacy of Probiotic Against Functional Constipation

This project aims to study the benefits of probiotic in modulating gut microbiota and treating functional constipation in patients aged 18-81.

18 - 60 years of age All Phase 2

Sacral Neuromodulation as Treatment for Chronic Constipation

The objective of this study is to study if low level laser therapy will do more good than harm for patients with severe chronic refractory constipation. It is a proof of concept study without a placebo arm.

6 - 70 years of age All Phase N/A

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