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constipation Clinical Trials

A listing of constipation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 66 clinical trials
G Ghassan Kassab, PhD

Fecobionics in Biofeedback Therapy in Dyssynergia Patients

Constipation affects 12-19% of Americans. Pelvic floor dyssynergia is considered to play an important role in constipation but the underlying mechanisms are not well understood in individual patients. The investigators have developed a novel device named Fecobionics that provide detailed mapping of physiological parameters during defecation. The aim of the …

21 - 75 years of age Both Phase N/A
C Christopher P Cardozo, M.D.

Transdermal Administration by a Novel Wireless Iontophoresis Device

Persons with spinal cord injury (SCI) have neurogenic bowel disorders which is associated with significant morbidity. The negative impact of bowel complications is often at the top of the list of problems reported by persons with SCI. Despite the magnitude of the problem of bowel dysfunction in persons with SCI, …

18 - 89 years of age Both Phase N/A

Preop Laxatives in Robotic Urologic Surgery

Minimally-invasive surgery, either laparoscopic or robotic, is commonly used in urology. Several urologic procedures including prostatectomy, radical nephrectomy, and partial nephrectomy are now commonly performed robotically. Patients undergoing these procedures often have delayed return of bowel function and persistent gastrointestinal symptoms including nausea/vomiting, abdominal distension, and bloating for several days …

30 - 100 years of age Both Phase 4
E Erhan Kızmaz, PhD

Visceral Osteopathy in Functional Constipation

It is a functional bowel disease characterized by excessive straining during defecation, infrequent defecation, and the feeling of incomplete evacuation. There are very few studies investigating the incidence and prevalence of functional constipation.Non-pharmacological treatment methods, including lifestyle changes, are primarily recommended for the treatment of constipation. The aim of the …

18 - 100 years of age Both Phase N/A
F Fan Zheng, MD

Efficacy of Probiotic Against Functional Constipation

This project aims to study the benefits of probiotic in modulating gut microbiota and treating functional constipation in patients aged 18-81.

18 - 60 years of age Both Phase 2

Sacral Neuromodulation as Treatment for Chronic Constipation

The objective of this study is to study if low level laser therapy will do more good than harm for patients with severe chronic refractory constipation. It is a proof of concept study without a placebo arm.

6 - 70 years of age Both Phase N/A
P PING YIN

Acupuncture for Functional Constipation in Older Adults

Through a scientific and standardized randomized controlled study, we observe the effectiveness and safety of acupuncture in the treatment of functional constipation in the elderly through the method of "nourishing kidney and dredging Fu organs".

60 - 80 years of age Both Phase N/A
A Andrew Shubov, MD

Transcutaneous Electrical Acupoint Stimulation (TEAS) for Chronic Constipation

Transcutaneous electrical acupoint stimulation (TEAS) is an emerging technology for non-invasive neuromodulation that has broad potential implications and warrants further study. The investigators' clinical experience from the University of California, Los Angeles (UCLA) Center for East-West Medicine (CEWM) has also demonstrated that TEAS can be used as an effective self-care …

18 - 100 years of age Both Phase N/A
F Filip de Vos, Dr.

Prevention of Opioid-induced Constipation in Patients With Advanced Cancer

More than 70% of patients with cancer in the palliative phase have pain that often requires treatment with opioids (morphine-like agents). Constipation occurs in 59% of patients treated with opioids. Opioid-induced constipation (OIC) has consequences that range from daily discomfort with social insecurity and disability to intestinal obstruction. It leads …

18 - 100 years of age Both Phase 4
W Weidong Tong, MD, PhD

STOPS Trial: Total vs Subtotal Colectomy for Slow Transit Constipation

Total colectomy with ileorectal anastomosis is a traditional surgical option for slow transit constipation. Subtotal colectomy with caecorectal anastomosis is suggested to be a superior approach. However, the optimal surgical option for slow transit constipation (STC) is controversial.

18 - 80 years of age Both Phase N/A

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