Advanced Filters
noise

constipation Clinical Trials

A listing of constipation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 90 clinical trials
C Can LAFÇI, PhD(c)

Prevention of Constipation in Cancer Patients

Constipation is the third most common symptom in patients undergoing chemotherapy, with an incidence rate ranging from 31% to 90%. Despite its high prevalence and adverse effects on patients, constipation is often not reported by patients and is not frequently monitored by nurses, resulting in delays in treatment and care. …

18 years of age All Phase N/A
Y Ying Wu, Dr.

Probiotics for Alleviating Functional Constipation in Adults

To investigate the clinical effects of probiotics in relieving chronic constipation in adults, and evaluate the improvement of symptoms in patients with constipation as well as their impacts on gastrointestinal function, immunity, and gut microbiota.

18 - 70 years of age All Phase N/A
A Alex Bortolotti

MowOot and Trans-anal Irrigation fOr coNstipation

This prospective, open-labelled, longitudinal, controlled study aims to evaluate the suitability of Intermittent Colonic Exoperistalsis (ICE) treatment for adults with refractory chronic constipation who are awaiting trans-anal irrigation (TAI). The ICE treatment will be applied using the MOWOOT device (USMIMA). The study involves two treatment groups: an experimental group receiving …

18 years of age All Phase N/A
F Faming Zhang, MD, PhD

Washed Microbiota Transplantation for Chronic Constipation in Adults

This is a single-center, randomized, double-blind, placebo-controlled, dose-exploring clinical study to explore the safety and efficacy of washed microbiota transplantation (WMT) for patients with chronic constipation.

18 - 70 years of age All Phase 1/2
L Linda Zhong, PhD

Electro-acupuncture for Irritable Bowel Syndrome With Constipation

The aim of the clinical trial is to evaluate the efficacy and safety of electro-acupuncture for irritable bowel syndrome with constipation (IBS-C) patients. 60 IBS-C patients will be randomized and allocated to either the electro-acupuncture arm or the sham acupuncture arm. We hypothesize that electro-acupuncture would result in superior symptom …

21 - 65 years of age All Phase N/A

Effect of Abdominal Massage Versus Visceral Manipulation on Constipation

The study compares the effect of abdominal massage vs. visceral manipulation on constipation status and quality of life in adults. Chronic idiopathic constipation (CIC) is considered a common functional bowel disorder characterized by difficult, infrequent, and/or incomplete defecation. It has a great impact on the quality of life and on …

20 - 40 years of age All Phase N/A
G Giovanni Cammarota

Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome With Constipation

Irritable bowel syndrome (IBS) is a complex multifactorial functional disorder, whose pathophysiology is largely associated to an impairment of the intestinal microbiota composition, namely dysbiosis. Thus, the modulation of the gut microbiota has been proposed as a possible therapeutic strategy for IBS patients alongside with current available drugs. Fecal microbiota …

18 years of age All Phase N/A
G Giovanni Cammarota

Fecal Microbiota Transplantation to Relieve Symptoms of Irritable Bowel Syndrome Without Constipation

Irritable bowel syndrome (IBS) is a complex multifactorial functional disorder, whose pathophysiology is largely associated to an impairment of the intestinal microbiota composition, namely dysbiosis. Thus, the modulation of the gut microbiota has been proposed as a possible therapeutic strategy for IBS patients alongside with current available drugs. Fecal microbiota …

18 years of age All Phase N/A
D Diane S Mendoza-Sarmiento, Ph.D in Health Research

Efficacy of LcS-Fermented Milk on Constipation-Related Symptoms in Filipino Adults

The primary purpose of this study is to investigate whether the consumption of a probiotic drink (with Lacticaseibacillus paracasei strain Shirota (LcS)) relieves constipation-related symptoms of Filipino adults, specifically its effect on stool consistency, frequency, and duration, and on gastrointestinal discomfort.

18 - 59 years of age All Phase N/A

Low FODMAP Plus PEG 3350 for the Treatment of Patients With Irritable Bowel Syndrome-Constipation

Consecutive patients with Irritable Bowel Syndrome with Constipation (IBS-C) will be recruited from the outpatient clinics of the University of Michigan Health System. Eligible patients will be asked to participate in a study that will test the efficacy the PEG 3350 + a diet low in fermentable oligo, di, monosaccharides, …

18 years of age All Phase N/A

Simplify language using AI