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scar-tissue Clinical Trials

A listing of scar-tissue medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 89 clinical trials
R Renata D. Lemos, MD, MMed

Use of Botulinum Toxin A in Direct Eyebrow Lift Scar

Prospective, controlled and randomized study in which participants indicated for surgery to direct eyebrow lift will be randomized into two groups. In addition to surgery, the patients will be treated with botulinum toxin in one eyebrow and saline (placebo) in the other site. The patients participate as treatment and placebo …

18 - 100 years of age Both Phase 2
J Jiayuan Zhu

Tissue-engineered Skin Graft Repair of Autologous Scar Dermal Scaffolds

Hypertrophic scar is an inevitable outcome of wound repair. It affects the appearance and some scar contracture often leads to joint dysfunction.Patients have low quality of life, long treatment cycle, heavy social burden and high medical costs.Skin grafting is currently the gold standard for scar repair.However, there are often insufficient …

- 80 years of age Both Phase N/A
D Daniel Eisen, MD

Aesthetic Outcome of Tie-over Bolster Application in Surgical Wounds

When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring. Several studies have been done to test ways to close wounds that reduce scarring. One idea …

18 - 100 years of age Both Phase N/A
D Daniel Eisen, MD

Pinch Grafting Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects on the Scalp

Oftentimes, following surgery on the scalp, wounds are left to heal by themselves. This is called "second intention." Open wounds left to heal on the scalp often take 8 weeks or more to completely heal. The investigators are investigating how second intention closure compares to another established reconstruction technique, called …

18 - 100 years of age Both Phase N/A
D Daniel Eisen, MD

Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds

When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring. Several studies have been done to test ways to close wounds that reduce scarring. The most …

18 - 100 years of age Both Phase N/A
D Daniel Eisen, MD

Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects

The purpose of this study is to determine the potential influence of sun protection on the aesthetic outcome of post-surgical scars following the reconstruction of Mohs micrographic surgery defects via linear repair. This study will be performed as a randomized split-wound study. Half of the wound will be treated with …

18 - 100 years of age Both Phase N/A

Silicone Taping for the Improvement of Abdominal Donor Site Scars

This study will look at silicone tape compared to the current no dressing standard at the investigators institution, to determine if silicone tape provides a significant improvement in post-abdominoplasty scar appearance. Silicone tape will be added to half of the abdominoplasty incision of patients undergoing abdominally-based breast reconstruction procedures two …

18 - 65 years of age Both Phase N/A
M Mohammadreza Pourahmadi, Ph.D., Postdoc Research Fellow

Effectiveness of Dry Needling in Linear Scar Tissue

Scar tissue can cause serious complications that significantly impact a patient's quality of life. Common complications include stiffness and contractions, which can restrict joint mobility and make daily activities challenging. In severe cases, these limitations can even prevent patients from fulfilling their work responsibilities or engaging in activities they enjoy. …

20 - 60 years of age Both Phase N/A
J Jewel Medley

Dose Regimen Study of SLI-F06 in Healthy Volunteers

Multi-center, dose-regimen, double-blind study evaluating the safety and efficacy of 4 doses of SLI-F06 compared with vehicle for improvement in scar appearance

18 - 65 years of age Both Phase 2
G Gina-Marie Cerantola, BSc, DPT

Optimizing Postpartum Pelvic Health Through Self-Scar Tissue Massage of Episiotomy and Perineal Scar Tissue A Pilot RCT

The goal of this Pilot Randomized Control Trial (RCT) is to determine if a larger RCT evaluating the effect of self-scar tissue massage of episiotomy and/or vagina/perineal tear scar tissue on pelvic health outcomes is feasible. The main questions it aims to answer are: Can the investigators recruit 130 participants …

18 - 100 years of age Female Phase N/A

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