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scar-tissue Clinical Trials

A listing of scar-tissue medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 102 clinical trials
A Anika Jallorina

Non-Ablative Laser to Treat Scarring Alopecia With Hair Follicle Gene Expression Analysis

The goal of this clinical trial is to evaluate the effectiveness of a non-ablative 1470 nm laser in treating scarring alopecia in adults. The study will also investigate the biochemical molecular pathways involved in laser therapy by analyzing hair follicle gene expression before and after laser treatment. The main questions …

18 years of age All Phase N/A
J Jennifer Barillas

Fractional Radiofrequency for Reduction of Surgical Scar Formation

Safety and Efficacy of Fractional Radiofrequency for the Reduction of Surgical Scar Formation

21 - 75 years of age Female Phase N/A
C Carol K Dingee, MD, FRCSC

Cosmetic Outcome of Electrocautery, Scalpel and PEAK PlasmaBlade for Surgical Breast Incisions

This study will compare the cosmetic scar result from the use of scalpel, electrocautery, and pulsed electron avalanche knife (PEAK) PlasmaBlade (PPB) for the initial skin incision for total mastectomy procedures without immediate breast reconstruction. It is hypothesized that there will be no significant difference in mastectomy scar cosmesis. The …

years of age All Phase N/A
K Karen A Giddens

Peri-Procedural Transmural Electrophysiological (EP) Imaging of Scar-Related Ventricular Tachycardia

Ventricular tachycardia (VT) contributes to over 350,000 sudden deaths each year in the US. Malignant VTs involve an electrical "short circuit" in the heart, formed by narrow channels of surviving tissue inside myocardial scar. An important treatment is to use catheter ablation to "block" the channel that forms the circuit. …

18 - 85 years of age All Phase N/A

Phase 3 Study of KP-100LI in Subjects With Vocal Fold Scar

The purpose of this study is to confirm the efficacy and safety of KP-100LI, a intracordal formulation containing recombinant human dHGF as the active pharmaceutical ingredient, for voice function improvement therapy in patients with vocal fold scar (including vocal fold sulcus).

18 - 75 years of age All Phase 3
A Aysa Ostovaneh

High Relaxivity Contrast Agent for Cardiac MR in the Myocardial Scar Assessment

Elucirem (Gadopiclenol) is a new macrocyclic gadolinium-based contrast agent (GBCA) with high relaxivity indicated for use in adults and children aged 2 years and older for contrast-enhanced magnetic resonance imaging. The product was approved in 2022 by FDA to be used to detect and visualize lesions with abnormal vascularity in …

21 years of age All Phase 4
J Justin P Gawaziuk, MSc

The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has …

18 - 60 years of age All Phase N/A
J Justin P Gawaziuk, MSc

The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.

18 - 60 years of age All Phase N/A
Y Yuqi Wang, Doctor

The Relationship Between Scar Formation and ESD Depth in Therapy for Gastric Carcinoma

This study is a single-center, prospective, group-controlled clinical trial, aiming to clarify the relationship between the depth of dissection and scar formation in the treatment of early gastric cancer by ESD, and to provide high-quality evidence-based medicine for the treatment of early gastric cancer.

18 - 75 years of age All Phase N/A
E Eue-Keun Choi

SCAR Burden of Left Atrium Guided cathEter Ablation sTrategy for Persistent Atrial Fibrillation

This is a multicenter, randomized controlled trial to compare the recurrence of 1-year atrial arrhythmia after catheter ablation of atrial fibrillation (AF) between pulmonary vein isolation (PVI) and PVI with additional left atrial (LA) substrate modification based on the left atrial low-voltage area (LA LVA) in patients with persistent AF …

19 years of age All Phase N/A

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