Advanced Filters
noise

heart-disease Clinical Trials

A listing of heart-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,908 clinical trials
C Christine Quast, MD

Phenotyping Heterogeneity and Regionality of the Aorta

The aorta distributes cardiac stroke volume into the whole body through its finetuned conductance function, that is propagation and modulation of flow pattern. Physicomechanic properties of the aortic wall assure continuous and homogenous blood flow distribution to organs. The physicomechanic properties of the aortic wall are heterotopic: The collagen/elastin ratio …

18 years of age All Phase N/A
P Philipp Lenz, Prof. Dr. med.

Implementing Spiritual Care in Inpatient Palliative Care

The goal of this observational study is to is to ascertain the spiritual needs of palliative patients in a standardized manner using the Spiritual Needs Questionnaire and to promptly address those needs by (specialized) spiritual care. To determine whether the effort of implementing the Spiritual Needs Questionnaire on a sustainable …

18 years of age All Phase N/A
V Valentina Paucke

Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures, Third Wave

The CLIMATE-III Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and benefit perception, self-efficacy, health literacy, and the degree of urbanisation of the patients' administration district are associated with these effects. Study …

18 years of age All Phase N/A
J Jieqiong Song

The Diagnostic and Prognostic Value of Speckle Tracking Imaging in Septic Cardiomyopathy

The aim of this study is to explore if STI technology, especially TMAD, plays an important role in evaluating left ventricular longitudinal systolic function and discriminating SICM in patients with sepsis. The investigators also intend to prove that TMAD may have predictive value in patients with sepsis, which is worthy …

18 years of age All Phase N/A

Sepsis in the ICU-II

Sepsis-induced cardiac dysfunction (SIMD) is a well-known phenomenon yet its diagnosis remains elusive with no accepted definition, or defining pathophysiological mechanism associated with this disease. Systolic dysfunction occurs in 20-70% of patients, and may be severe, yet does not appear to have any prognostic value for mortality. Diastolic function has …

18 years of age All Phase N/A

Role of Aortic Valve Composition in Pathophysiology and Diagnosis of Aortic Stenosis

The study aims to evaluate composition differences of aortic valves in different stages and phenotypes of aortic stenosis using non-invasive imaging and histology.

18 years of age All Phase N/A
E Eduard Charchyan, professor

Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation

Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle …

18 years of age All Phase N/A

Frailty, Physical Capacity and Lung Function in Postoperative Cardiac Surgery Patients

The goal of this observational and prospective study is to investigate changes in physical performance, lung function, and respiratory and peripheral muscle strength in patients during the postoperative period following coronary artery bypass grafting (CABG) and valve replacement surgery..

18 years of age All Phase N/A
D Dave Newby

Non-invasive Coronary Thrombus Imaging to Define These Cause of Acute Myocardial Infarction

We now have very sensitive blood tests that can pick up damage to the heart and find patients who have had a heart attack. However, whilst this is welcome, it does not identify what causes the heart attack and can sometimes pick up other conditions that cause a strain on …

18 years of age All Phase N/A
Z Ziren Tang, MD

Resting Energy Expenditure and Substrate Consumption in Cardiac Arrest Patients Under Target Temperature Management

This study is a single-center, prospective, observational study. According to the sample size formula, an estimated 40 cases should be collected, all of whom are from the emergency intensive care unit. After successful cardiopulmonary resuscitation, the enrolled patients will be transferred to the emergency intensive care unit for further standardized …

18 years of age All Phase N/A

Simplify language using AI