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heart-disease Clinical Trials

A listing of heart-disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,908 clinical trials

Pattern of Cardiac Arrhythmia in Patients With MASLD

Study the relationship between patients with MASLD and cardiac arrhythmia that could be occur in thos patients

18 years of age All Phase N/A
J Jesus Gil

EluPro Antibiotic-Eluting BioEnvelope Registry

A Multi-Center Registry Study Evaluating Participants Who Receive EluPro Antibiotic-Eluting BioEnvelope During CIED Implantation

18 years of age All Phase N/A
O Osama Soliman, MBBCH, PHD

Understanding CARdiac Events in Breast Cancer

In Ireland, over 3,000 patients are diagnosed with breast cancer annually, and 1 in 9 Irish women will be diagnosed with breast cancer in their lifetime. There is evidence that female breast cancer survivors are more likely to die of cardiovascular disease than their age-matched counterparts. This research is focused …

18 - 90 years of age Female Phase N/A
S Sanna Gunnarstein

Absolute Coronary Flow in Patients With Heart Failure With Reduced Ejection Fraction and Left Bundle Branch Block With Cardiac Resynchronization Therapy

Cardiac resynchronization therapy (CRT) is an effective therapeutic strategy in patients with symptomatic heart failure (HF) patients with LVEF of ≤35% and left bundle branch block (LBBB). However, approximately one-third of CRT-recipients do not improve after therapy (non-responders), despite meeting the required criteria. Previous studies have documented that the positive …

18 years of age All Phase N/A
Y Yi Xu

An Evaluation of the KCCQ Score in Predicting Cardiovascular Risk in Dialysis Patients

Cardiovascular Disease (CVD) is the main complication and the most important cause of death in CKD patients. As the disease progresses, the incidence of cardiovascular disease in CKD patients gradually increases, especially in End-Stage Renal Disease (ESRD) patients receiving dialysis treatment, where the prevalence of cardiovascular disease reaches its highest …

18 years of age All Phase N/A
C Christoph Gräni, MD PhD

European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries

Anomalous aortic origin of a coronary artery (AAOCA) is a group of rare congenital heart defects with various clinical presentations. The lifetime-risk of an individual living with AAOCA is unknown, and data from multicentre registries are urgently needed to adapt current recommendations and guide optimal patient management. The European Registry …

years of age All Phase N/A
L Lihong Xu, B.N.

Efficacy and Safety of Comprehensive Treatment in Patients With IR-CAD: a Self-controlled Cohort Study

This is a self-controlled cohort study to evaluate the efficacy and safety of comprehensive treatment in patients with inflammation-associated rapidly-progressive coronary artery disease (IR-CAD) by comparing the study endpoints before treatment with those after treatment in the same group of patients.

18 years of age All Phase N/A

MRI to Predict Rejection and Failure in Transplant and Cardiomyopathy Patients

Overall Research Strategy of this protocol is to refine and validate noninvasive CMR imaging sequences with invasive hemodynamic and pathology results to create a comprehensive, noninvasive, radiation-reduced regimen for pediatric cardiomyopathy and cardiac transplant assessment. We were the first to perform MR-guided cardiac catheterization in US children, and have accumulated …

6 years of age All Phase N/A
L Lihong Xu, B.N.

Disease Characteristics of IR-CAD: a Case-control Study

The present case-control study is designed to investigate the disease characteristics of IR-CAD by comparing the demographics, clinical features, lab results, imaging findings, and prior treatment between 20 patients with IR-CAD and 10 patients with AS-CAD.

45 - 64 years of age All Phase N/A
D Daniel DA SILVA, Md

Predictive Outcome in Comatose Patients

Evaluating the prognosis of comatose patients after cardiac arrest (CA) in the intensive care unit (ICU) remains challenging. It requires a multimodal approach combining standardized clinical examination, serum biomarkers, imaging and classically electrophysiological examinations, (among them auditive evoked potentials or AEP) but none has a sufficient sensitivity/specificity. In a preliminary …

18 years of age All Phase N/A

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