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urinary-incontinence Clinical Trials

A listing of urinary-incontinence medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 147 clinical trials
A Alexia DeOliveira

Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women

The goal of this clinical trial is to learn if a vaginal radiofrequency (RF) device called MORPHEUSV works to treat overactive bladder (OAB) in women. Researchers also want to learn how safe the device is for this indication. This study will include women ages 22 to 80 who have had …

22 - 80 years of age Female Phase N/A
H Hui-Hsuan Lau, PhD

Efficacy/Safety of Midurethral Sling

The trans-obturator tape (TOT), which exhibits a satisfactory cure rate and a relatively diminished invasiveness, has been increasingly accepted as a surgical treatment of stress urinary incontinence (SUI) patients. Nevertheless, in contrast to the well-recognized therapeutic benefit of the enhanced resistance to the bladder continence during urine storage, if the …

30 - 100 years of age Female Phase N/A
S Sierra Williams

ProACT Post-Approval Study

The ProACT Post Approval Study is a 5-year prospective, open-label, multi-center study designed to evaluate the long-term incidence of urethral stricture and device erosion after ProACT implantation. In addition, the study will evaluate whether treatment with ProACT affects clinical outcomes after subsequent SUI therapies.

50 years of age Male Phase N/A
A Angela Waldvogel, RN

Effect of Peri-Urethral Stimulation on Intra-Urethral Pressure

The purpose of this early feasibility prospective study is to gain initial understanding of the effect of acute peri-urethral neurostimulation on the perineal nerves on intra-urethral pressure.

18 years of age Female Phase N/A
M Mohamed F Salman, MD

Laparoscopic Burch Colposuspension Versus Modified Burch Colposuspension

This study aims to compare the success rate and complications following laparoscopic standard Burch colposuspension and laparoscopic modified Burch colposuspension (Transobturator tape like)

18 years of age Female Phase N/A

Impact of Unrestrictive Exercise Following Mid-Urethral Sling Surgery

To determine the impact of unrestricted postoperative activity on intermediate- and long-term continence outcomes of mid-urethral sling surgery in women with stress urinary incontinence. To assess the natural return to baseline activity level when patients are unrestricted following mid-urethral sling surgery with or without concomitant anterior or posterior pelvic organ …

18 years of age Female Phase N/A
N Nicholas Bossaller

Desara ® One Single Incision Sling 522 Study

A post-market study to compare the safety and effectiveness of the Desara® One Single Incision Sling (SIS), when compared to that of an FDA cleared transobturator sling over a period of 36 months.

18 years of age Female Phase N/A
T Tess Gao, MD

The Effectiveness of Prophylactic Antibiotics for Urethral Bulking

The goal of this clinical trial is to evaluate if prophylactic antibiotics in urethral bulking are effective in reducing postprocedural urinary tract infections.

18 years of age Female Phase N/A
A Anne-Marie Lake, MSc.

Managing Impact-related Leakage During Exercise Using Intravaginal Support

The goal of this study is to evaluate the effectiveness of using a regular menstrual tampon or a Uresta pessary to reduce urine leakage associated with running-induced stress urinary incontinence (RI-SUI) in females aged 18 and older. Secondly, the study aims to assess whether either intervention mitigates transient changes in …

18 years of age Female Phase N/A
S Susanne Taege, MD

Assessing the Utility of Prophylactic Antibiotics at Time of Urethral Bulking Using Bulkamid (Bulkamid Study)

The primary aim of this study is to assess the utility of prophylactic oral antibiotics at time of Bulkamid transurethral bulking to reduce the incidence of urinary tract infection (UTI) in the immediate postoperative period. The secondary aims of the study include assessing UTI rates and success rates if patients …

18 - 50 years of age Female Phase 4

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