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urinary-incontinence Clinical Trials

A listing of urinary-incontinence medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 143 clinical trials

Topical Vaginal Estrogen for Postpartum Obstetric Anal Sphincter Injury Recovery

Obstetric anal sphincter injuries (OASIS) cause significant morbidity and are well known risk factors for sexual dysfunction, urinary and anal incontinence. Postpartum and breastfeeding are relative hypoestrogenic states with risk factors for dyspareunia and vaginal atrophy. Estrogen deficiency results in changes in the vaginal epithelium and poor tissue quality which …

18 - 100 years of age Female Phase 4
K Kathleen Vincent, MD

Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries

The goal of this study is to determine whether administration of sildenafil will decrease urine leakage in patients with spinal cord injuries.

18 - 70 years of age Both Phase 2
K Karin Gustafsson, MD

Multicenter Study for Diagnosis and Treatment of Perianal Abscesses

Drainage of perianal abscesses is a well established treatment. Traditionally its been done in general anesthesia after the swelling has been localised its been drained with a knife. After surgical intervention complications can occur with recidivism, chronic fistulas that go from the anal to the skin and sometimes the anal …

18 - 100 years of age Both Phase N/A
O Omnia Nassar, Dr

Desmopressin Monotherapy for Monosymptomatic Nocturnal Enuresis

Nocturnal Enuresis (NE) is defined as the involuntary passage of urine during sleep past the age of usual control, which is considered a developmental age of 5 to 7 years. NE is a common problem that causes distress to both children and their families. It has an adverse impact on …

7 - 14 years of age Both Phase N/A
A Amy Nelson, MA, CCRC

F15 Recharge Free Axonics SNM System Clinical Study

Multicenter, prospective, non randomized, single arm evaluation of patients with overactive bladder (OAB) and/or fecal incontinence (FI) employing the Axonics recharge free SNM System.

18 - 100 years of age Both Phase N/A
M Meryam El Issaoui, MD

The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder

The purpose of this study is to investigate the effect of Lidocaine solution versus placebo (isotonic Sodium Chloride NaCl) disposed inside the urinary bladder as intravesical anesthesia prior to onabotulinum toxin A injections in the treatment of urgency urinary incontinence.

18 - 100 years of age Female Phase 3
B Brenda Romeo, CCRC

Optimal Pulse Width Used in Transcutaneous Electrical Nerve Stimulation for Treating Nocturnal Enuresis in Children

Children referred to pediatric urology clinic for primary nocturnal enuresis will be screened for enrollment. Patients who fail will next be offered therapy with a bedwetting alarm device or a TENS unit as an alternative, and those who chose TENS therapy will be included in the study.The patients will be …

5 - 17 years of age Both Phase N/A

A Randomized Controlled Trial of Electrical Stimulation to Treat Pelvic Floor Disorder

Female pelvic floor disorders (PFDs) include urinary incontinence,pelvic organ prolapse (POP), and fecal incontinence-which often occur together. Pelvic floor disorders impair multiple aspects of the life quality, including the sexual function of women. Surgery became the first choice of treatment, however, and not until 1980s was the renewed interest in …

20 - 75 years of age Female Phase N/A

Physical Therapy for Men Undergoing Prostatectomy

The purpose of this study is to determine if pelvic floor muscle training with a physical therapist before and after surgery will improve health-related quality of life following robot-assisted radical prostatectomy.

18 - 100 years of age Male Phase N/A
S SITU Trials Unit

Focal Therapy for Prostate Cancer Using HIFU

RATIONALE: Prospective trials using hemi-ablation with high intensity focused ultrasound (HIFU) (Sonablate 500) have demonstrated feasibility, safety, and encouraging functional outcomes and early cancer control with 90% of men achieving trifecta status (no erectile dysfunction, leak-free pad-free continence, cancer control). However, these trials have involved small numbers of patients with …

- 90 years of age Male Phase N/A

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