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Mechanical Ventilation Clinical Trials

A listing of Mechanical Ventilation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 136 clinical trials
E Emilio Steinberg, RT

Ventilatory Settings and Monitoring Variables Associated With Weaning Failure in Critically Ill Patients

Mechanical ventilation (MV) is essential in managing acute respiratory failure. Its duration is a crucial aspect since both, unnecessary prolongation and premature withdrawal have deleterious effects on patient outcomes in the ICU. The process of weaning refers to the set of procedures and evaluations carried out to discontinue MV. Regardless …

18 - 100 years of age All Phase N/A

Mechanical Ventilation on Hippocampus

Ventilator-associated brain injury (VABI) frequently occurs in ICU patients. Although animal studies indicate the hippocampus as a key target of VABI, its relevance in human patients remains uncertain. In this study, the investigators aim to monitor hippocampal EEG activity during the weaning process of patients off mechanical ventilation, and also …

18 years of age All Phase N/A
M Mohan Gurjar, MD, PDCC

Cytomegalovirus Reactivation in ICU Patients Requiring Prolong Mechanical Ventilation

Cytomegalovirus (CMV) is a latent infection virus that is widespread in the population. CMV may reactivate under certain circumstances, and its hazardous nature has been proven, especially in immunosuppressed patients. However in recent years, some studies have found that CMV reactivation also exists in apparently immunocompetent patients during their critical …

18 - 80 years of age All Phase N/A
K Ke-Yun Chao, PhD

Pressure-Sensing Mattresses and Mechanical Ventilation Weaning in Neonatal

This study aims to explore the correlation between using ballistocardiography for monitoring respiration and heart rate in neonates under invasive and non-invasive respiratory support.

- 1 years of age All Phase N/A
M Merve Yazici Kara

Effect of Mechanical Ventilation on Radiofrequency Ablation in Atrial Fibrillation

Radiofrequency ablation (RFA) for atrial fibrillation (AF) is performed under general anesthesia. The success of the procedure depends on the safe contact of the catheter electrode with the myocardium. Movement of the catheter tip due to respiratory changes can result in inadequate lesion formation and AF recurrence. The success of …

18 years of age All Phase N/A

Intraabdominal Hypertension and Occurrence of Microaspiration in Cirrhotics Under Mechanical Ventilation

The study aims to demonstrate the relationship between intra-abdominal hypertension (IAH) and abundant microaspirations in mechanically ventilated cirrhotic.

18 - 99 years of age All Phase N/A

Polygraphy at Home for Neuromuscular Patients Under Non-invasive Mechanical Ventilation

The primary objective of the study is to evaluate the feasibility, the quality and the utility of a polygraphic control at home in order to appreciate the efficacy of the night time non-invasive ventilation (allowing to optimize the ventilator settings when the results are not satisfactory).

18 years of age All Phase N/A
W Willem Snoep, BSc

Calibration of Esophageal Balloon Catheter in Spontaneous and Mandatory Mechanical Ventilation

Calibration of the esophageal balloon catheter (Pes catheter) is important for the right measurement of the esophageal pressure (Pes) and subsequent interpretation of the derived transpulmonary pressures during mechanical ventilation. Both relative changes and absolute values of Pes can be affected by inappropriate filling of the esophageal balloon and by …

18 years of age All Phase N/A
F Francois Lellouche

Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation

When mechanical ventilation is initiated, a humidification method should be chosen. There is two methods: heat and humidity exchanger filters or heated humidity. The second method is recognized to be more efficient, but many external factors can influence its performance. Insufficient humidity results in observable problems, such as difficult management …

18 years of age All Phase N/A
S Sonal Pannu

Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).

The aim of this study is to identify and determine the levels of oxidized lipids and lipid mediators following exposure to oxygen supplementation during mechanical ventilation by oxidative lipidomics. The investigators will include patients with mechanical ventilation and have received FiO2=>0.5 atleast 90 minutes and collected two sequential mini bronchoalveolar …

18 - 110 years of age All Phase N/A

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