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Anesthesia Clinical Trials

A listing of Anesthesia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 564 clinical trials
H Hosam Hanna, MD

Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use

The purpose of this study is to determine whether an injection of a local anesthetic (Bupivacaine with epinephrine) in the vaginal cuff prior to closure would result in less immediate postoperative pain medication and increase patient comfort/satisfaction.

18 years of age Female Phase 4

Opioid-free Anesthesia Protocol for Neurosurgical Supratentorial Tumor Resection

Opioids have many side effects, such as constipation, urinary retention, itchy skin, respiratory depression, and postoperative nausea and vomiting. These side effects can lead to delayed recovery, longer hospital stays, and increased health care costs. Opioid-free anesthesia is the combination of anti-nociceptive drugs to block the different pathways involved in …

18 - 65 years of age All Phase N/A
A Ahmed A Hashem, PhD

Risk of Nerve Damage After Administration of Local Anesthesia

This research aims to evaluate of the risk of nerve damage following the administration of articaine 4% and lidocaine 2% for Inferior Alveolar nerve Block (IANB). A Randomized Controlled Clinical Trial will be conducted where the patient will be randomly assigned to one the two groups; articaine 4% and Lidocaine …

18 - 55 years of age All Phase 1

Inhalational Agents Versus Dexmedetomidine for Maintenance of General Anesthesia

The climate crisis and environmental pollution are escalating day by day, making the reduction of carbon footprints increasingly important both on an individual and industrial level. Inhalational anesthetic agents are widely used in daily anesthesia practice. However, some of these agents are released into the environment either unchanged or as …

39 - 99 years of age All Phase N/A
D Dafna Ben Yehuda Raz, MD

Topical Anesthesia During Catheter Insertion for Cervical Ripening (TOLERANCE)

The goal of this RCT is to learn if application of topical anesthetic cream to the perineum and posterior wall of vagina prior to balloon catheter insertion as part of labor induction will reduce pain levels experienced by pregnant individuals. All participants are 18 or older, carrying a singleton in …

18 years of age Female Phase 4
M Migena DEMIRI, MD

Opioid Free Versus Opioid Based Anaesthesia for Free Flap Reconstruction Surgery of the Breast: A Phase III Multicentric Randomized Controlled Study.

This study will compare morphine consumption during the first 48 hours postoperatively between the OFA group and the CA control group.

18 years of age Female Phase 3
C Christian Rouphael, M.D.

Asleep Fiberoptic vs Direct Laryngoscopy Effect on Hemodynamic Stability Using Opioid Free Anesthesia Induction

The goal of this clinical trial is to compare blood pressure and heart rate between the fiberoptic and direct oral intubation using opioid free anesthesia induction. Secondary objectives include comparing the time needed for intubation and the incidence of postoperative sore throat, hoarseness, and upper airway trauma in adults aging …

18 - 55 years of age All Phase N/A

Impact of Propofol-Based Total Intravenous Anesthesia Versus Anesthesia With Sevoflurane on Long-term Outcomes With Patients Undergoing Elective Excision of Primary Liver Tumors

This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary Hepatocellular carcinoma. The study will enroll approximately 500 volunteers to compare the progression-free or overall survival in patients undergoing elective partial hepatectomy for primary liver tumors between propofol and sevoflurane for the …

20 - 80 years of age All Phase 4
S Seyeon Park

Effect of Local Warming for Arterial Catheterization in Pediatric Anesthesia

The increase in internal diameter (ID) and cross-sectional area (CSA) may facilitate better arterial catheterization. Since an increase in body temperature can cause peripheral vasodilation, we aimed to determine if local warming of the radial artery (RA) catheterization site could improve the success rate of catheterization in pediatric patients.

- 2 years of age All Phase N/A

NOL Guided Analgesia During Elective Laparoscopic Surgery Under General Anesthesia

The aim of this study is to investigate the hypothesis that the intraoperative use of the nociception level index NOL can reduce opioid consumption in adult patients undergoing elective laparoscopic surgeries under general anesthesia, as well as to explore its effect on post-operative pain and patient recovery.

18 - 70 years of age All Phase N/A

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