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Insulin Clinical Trials

A listing of Insulin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 544 clinical trials
S Study Coordinator

Denosumab for Type 1 Diabetes

Type 1 diabetes (T1D) arises from abnormal immune cell-mediated injury to beta cells that make insulin. The injured beta cells can then no longer make the needed amount of insulin to stay healthy. However, in the early stages of T1D, some beta cells are still alive and functioning. Treatment to …

18 - 50 years of age All Phase 1/2
B Beth Loots

InvesT1D: Promoting Adolescent Investment in Diabetes Care

The goal of this clinical trial is to see if a financial incentives program called InvesT1D is helpful to support diabetes management in adolescents with type 1 diabetes. Adolescent participants will be randomized to usual care or receive financial incentives for meeting diabetes self-management and clinical outcomes goals during the …

12 years of age All Phase N/A
D Dominque Forrest

An Adaptive Design Study of MTX228

MTX228 has been identified as a medication that might allow the re-growth of insulin producing beta cells in people with Type 1 Diabetes. Promoting the re-growth of lost beta cells would be beneficial to people with Type 1 Diabetes because it would allow them to take less insulin by injection …

18 - 65 years of age All Phase 2

Efficacy and Safety of Teplizumab in Japanese Participants With Stage 2 Type 1 Diabetes

This is a parallel, Phase 2, two-arm study to assess the efficacy and safety of 14-days intravenous (IV) infusion of teplizumab treatment. Teplizumab has been approved by FDA to delay the onset of Stage 3 Type 1 Diabetes (T1D) in adults and pediatric patients aged 8 years and older with …

8 - 34 years of age All Phase 2
S Sue Brown, MD

Safety and Feasibility of a Machine-Learning Bolus Priming Added to Existing Control Algorithm

A randomized crossover trial assessing glycemic control using Reinforcement Learning trained Bolus Priming System (BPS_RL) added to the the Automated Insulin Delivery as Adaptive NETwork (AIDANET algorithm) compared to the original AIDANET algorithm.

18 years of age All Phase N/A
A Alona Hamou, Msc

Carb Counting vs. Simplified Qualitative Meal-Size Estimation

The goal of this study is to compare qualitative meal-size estimation to accurate carb counting in adolescents with Type One Diabetes using all available AID (Automated Insulin Delivery) systems. We will compare glucose control parameters and patient related outcome measures between the groups. 120 children and adolescents with type 1 …

6 - 18 years of age All Phase N/A
L Lutgarda Bozzetto

Glycemic Response to Carbob-Enriched Pasta in Healthy and With Type 1 Diabetes People

Carob (Ceratonia siliqua) is a fruit traditionally used in various Mediterranean countries for the preparation of sweets and beverages. Its pulp, once the seeds are removed, is milled into carob flour, a nutrient-rich food containing fiber, carbohydrates, proteins, and essential minerals such as potassium, magnesium, sodium, phosphorus, and calcium. Carob …

18 - 50 years of age Male Phase N/A
L Louis Potier, Dr

The Effect of Hedia Diabetes Assistant on TiMe-in-range in People With Type 1 Diabetes and Sub-Optimal Glycemic Control in France - A Randomised Controlled Trial.

The goal of this randomized controlled study is to assess the clinical performance and safety of Hedia Diabetes Assistant in adults with type 1 diabetes and suboptimal glycemic control in France. The main question to answer is: Does Hedia Diabetes Assistant improve glycemic control? Researchers will compare Hedia Diabetes Assistant …

18 years of age All Phase N/A
C Christina M Andersen, PhD

Use of an Online Intervention for the Treatment of Diabetes Distress in Patients With Type 1-Diabetes

This study will investigate whether an online intervention can be helpful in reducing diabetes distress in people with type 1 diabetes and elevated diabetes distress, compared to individual counselling sessions (online, phone-based or face-to-face, depending on the preference of the person with type 1 diabetes). Half of the participants will …

30 years of age All Phase N/A
B Brad J Thrasher, DO

Resistance Training in Type 1 Diabetes Mellitus

The purpose of this study is to learn how different resistance training programs affects blood sugar in young athletes with T1DM.

13 - 17 years of age All Phase N/A

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