Advanced Filters
noise

Insulin Clinical Trials

A listing of Insulin medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 523 clinical trials
M Menglu Zhang, PhD

Weight Cycling on Hyperandrogenemia and Insulin Resistance in Polycystic Ovary Syndrome

This study prospectively includes PCOS patients with normal weight and overweight/obesity, closely follows up and intensively manages them, and observes the level and distribution of weight reduction achieved by patients after lifestyle intervention (high-protein diet for weight loss). Additionally, it aims to provide reference for setting weight loss targets for …

18 - 45 years of age All Phase N/A
A Anne Sophie Sølling, MD, PhD

The Effect of Denosumab on Muscle and Strength and Insulin Sensitivity

Randomized, placebo controlled prospective trial evaluating the effect of denosumab on insulin sensitivity and muscle strength.

40 years of age Female Phase 4
M Megan Gangwish

Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)

The main purpose of research is to examine and understanding the development of hypertension in obese adults with insulin resistance. Findings from our studies will identify unique mechanisms that can be targeted to limit increases in vascular dysfunction and reduce the excessively high prevalence of hypertension and risk for cardiovascular …

35 - 65 years of age All Phase 1/2
E Ekrem M Ayhan, BS

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

This 12-week controlled diet and weight intervention study seeks to define the molecular pathways that link excess body weight to the development of insulin resistance (IR). Blood, adipose and stool are sampled at three timepoints; baseline, peak weight (4 weeks) and post weight loss to monitor changes in cellular processes. …

35 - 65 years of age All Phase N/A
J Jennifer Kalil, MD

Application of High-dose Insulin Therapy to Improve Liver Function and Regeneration

The primary objective of this interventional study is determine if the future liver remnant can be optimized by improving liver function pre-operatively in patients who are scheduled for major hepatectomy. The main questions it aims to answer are: Does high-dose insulin therapy improve liver function in the pre-operative setting? What …

18 years of age All Phase N/A
R Rafael Iglesias

Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease

This study will be evaluating the safety and efficacy of insulin and glutathione in subjects with Parkinson's Disease compared to placebo.

30 - 85 years of age All Phase 2
D Dalia I Halwag, PhD, MD

Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars

Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars. In addition, a lack of inclusion of a control group instead of comparing topical preparations with insulin was …

12 - 60 years of age All Phase N/A
X Xiaoying L Li

Artificial Intelligence-assisted Insulin System in Type 2 Diabetes in General Wards

Our study was a single-blind, randomised, controlled, multicentre study. The study was planned to include 140 patients admitted to the general ward for subcutaneous insulin therapy, who were randomly divided into two groups in the ratio of 1:1, one group with an artificial intelligence assisted insulin dosimetry system to adjust …

18 years of age All Phase N/A
M Marianna Wetherill, PhD

Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma

The NOURISH-OK Study will identify how food insecurity contributes to insulin resistance, an important surrogate marker of many co-morbidities in HIV disease, using an integrated framework to identify key leverage points for insulin resistance. Drawing from these pathways, this study will adapt and evaluate a community-driven, science-informed "food as medicine" …

18 years of age All Phase N/A

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

This is a Phase 3 trial of cadisegliatin as adjunctive therapy to insulin in participants with Type 1 Diabetes Mellitus.

18 years of age All Phase 3

Simplify language using AI