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Analgesia Clinical Trials

A listing of Analgesia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 448 clinical trials
C Chad Copeland

Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy

The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by FDA and on the market for post-surgical pain control. The investigators plan on randomizing study participants to either …

18 - 65 years of age All Phase N/A
W William Hakeos, MD

Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures

An open reduction and internal fixation is a painful procedure requiring intensive postoperative pain management. Traditionally, opioid analgesia has been the gold standard for postoperative pain control. However, given the harmful side effect profile and opioid epidemic in the United States, it is advantageous to use alternate forms of analgesia. …

18 - 80 years of age All Phase 4
N Nasser Al Khaldi, Senior Consultant Prostho

Dexamethasone (4 mg vs. 8 mg) for Pain Control in Dental Implant Surgery

This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site. Later, postoperative pain will be assessed using …

21 - 80 years of age All Phase 3
M Myung IL Bae

Effects of Analgesia Nociception Index (ANI)-Guided Analgesia on Postoperative Bowel Function.

Investigators will examaine the effects of Analgesia Nociception Index (ANI)-guided analgesia on postoperative bowel function recovery in laparoscopic colorectal surgery. This is a prospective randomized-controlled study. Investigators will randomly divide the patients into two groups. In ANI group, remifentanil infusion rate during anesthesia will be adjusted according to ANI monitoring. …

19 years of age All Phase N/A
M Malgorzata Domagalska, Ph.D.

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Hip Arthroplasty

Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for hip arthroplasty

18 - 100 years of age All Phase 4
r riadh boukef, professor

Enantyum® IV Versus Piroxen® IM in Emergency Pain Management

For pain of traumatic origin, the RICE protocol (Rest, Ice, Compression, Elevation) is the main therapeutic measure during the first 4 to 5 days post-trauma. However, there is currently insufficient evidence that this protocol is effective [4]. In the emergency department, paracetamol, NSAIDs or a combination of several molecules are …

18 - 85 years of age All Phase 3
M Malgorzata Domagalska, Ph.D.

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Spine Surgery

Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for spine surgery.

18 - 100 years of age All Phase 4
K Kelly Hendrickson

Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits

The primary aim of this implementation-effectiveness trial is to examine the effectiveness of Mindfulness-Oriented Recovery Enhancement (MORE) and patient-centered chronic pain management visits in primary care as interventions to reduce chronic pain, improve quality of life, and reduce opioid-related harms among chronic pain patients on long-term opioid therapy.

18 years of age All Phase N/A
M Mindy Rodden, PhD, RN, CPNP-AC

Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients

Adult patients with morbid obesity who have had Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (LSG) surgery have impaired drug metabolism. There is a paucity of information available on how these patients metabolize acetaminophen post operatively and if drug preparation has any effect on achieving adequate pain control. The …

18 years of age All Phase 2

Group-based Integrative Pain Management in Primary Care Safety Net Clinics

Socioeconomically disadvantaged populations have a high prevalence of chronic pain, exacerbated by social isolation, intersectional stigma, and disparities in pain assessment and treatment options. Effective interventions using a multilevel, biopsychosocial approach are needed to decrease the unequal burden of pain. The proposed study will test group-based integrative models of pain …

18 years of age All Phase N/A

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