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Kidney Transplant Clinical Trials

A listing of Kidney Transplant medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 211 clinical trials
V Vincent PERNIN, MD

Proteinuria in Renal Transplant Patients Treated With Dapagliflozin

The prevalence of chronic kidney disease is rising steadily and represents a major public health challenge. Hypertension and proteinuria are two factors strongly associated with the progression of chronic kidney disease (CKD) and the high risk of cardiovascular complications. Achieving blood pressure control and reducing proteinuria is therefore a major …

18 years of age All Phase N/A
C Cadence Baker

Prebiotic Therapy to Improve Outcomes of Renal Transplant

An investigator initiated pilot study: two arm, double blind, placebo controlled, randomized, group of approximately 60 patients undergoing a kidney transplant. Participants will be treated with human milk oligosaccharide (HMO) prebiotic versus placebo over 12 weeks from start of the investigational medication date (approximately 3 months) to test whether HMO …

18 years of age All Phase N/A
L Larissa Myaskovsky, PhD

Access to Kidney Transplantation in Minority Populations

Hispanic/Latino (HL) and American Indian (AI) patients are more likely than whites to have kidney failure, but less likely to complete transplant evaluation or receive a kidney transplant (KT), the best treatment for kidney failure. Using comparative effectiveness research methods, we will conduct a pragmatic randomized trial to compare the …

18 years of age All Phase N/A
D Dag Olav Dahle, MD PhD

Home Blood Pressure Monitoring in Kidney Transplant Recipients

Randomized controlled study of home blood pressure monitoring in kidney transplant recipients.

18 years of age All Phase N/A
M Mary Farnsworth

CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients

The purpose of this study is to study how CMVIG interacts with the body and to see if it might work to prevent kidney transplant patients from becoming infected with CMV.

18 - 70 years of age All Phase 1/2

One-month Latent Tuberculosis Treatment for Renal Transplant Candidates

This is a prospective, single-center, single-arm, open-label study investigating the safety, compliance and pharmacokinetics of 1-month treatment of Isoniazid, Rifapentine and Vitamin B6 in renal transplant candidates.

18 - 90 years of age All Phase 4
C Chul-Woo Jung, MD. PhD

Acute Pharmacokinetic-pharmacodynamic Change of Rocuronium After Reperfusion of Renal Graft

Reperfusion of renal graft in kidney transplantation can change the pharmacokinetic-pharmacodynamic (PKPD) parameters of rocuronium. The immediate increase of urine output during surgery may change the PKPD parameters of the drugs, including elimination rate. The goal of this study is to characterize the PKPD model of rocuronium during kidney transplantation …

18 - 60 years of age All Phase N/A
H Heather LaPier, BSc

Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2

OK-TRANSPLANT 2 is a vanguard study for a large randomized, pragmatic, open-label trial. We will randomize participants with obesity, high-risk CKD/dialysis who are hoping for lose weight for the purpose of kidney transplant. Subjects will either be enrolled on a virtual weight management program or continue their usual care.

18 years of age All Phase 4
T Teresa Conca, BSN

CardioRenal Effects of SGLT2 Inhibition in Kidney Transplant Recipients

CREST-KT is a single-center, double-blinded, randomized trial of empagliflozin therapy in 72 kidney transplant recipients with (n=36) and without type 2 diabetes (n=36). After evenly dividing patients by type 2 diabetes diagnosis, patients will be randomized 2:1 to empagliflozin 10mg versus placebo.

18 years of age All Phase 2
L L Wennberg, MD

Imlifidase Prior to Kidney Transplant in Highly Sensitised Children

The goal of this clinical trial is to learn about the efficacy and safety of imlifidase in highly sensitized paediatric patients, 1-17 years old, with end stage renal disease (ESRD). The main questions it aims to answer are: Does imlifidase treatment result in crossmatch conversion that enables transplantation? How is …

1 - 17 years of age All Phase 2

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